Sodium in PDB 3gzh: Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli

All present enzymatic activity of Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli:
4.3.2.2;

The structure of Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli, PDB code: 3gzh was solved by G.Kozlov, K.Gehring, Montreal-Kingston Bacterial Structural Genomicsinitiative (Bsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	77.316, 100.256, 150.104, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21.4

The binding sites of Sodium atom in the Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli (pdb code 3gzh). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli, PDB code: 3gzh:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:19.2 occ:1.00 O A:HIS50 2.5 35.1 1.0 O A:VAL56 2.5 35.6 1.0 O A:ILE53 2.6 33.9 1.0 O A:LEU47 2.9 25.4 1.0 O A:ALA48 2.9 30.6 1.0 C A:ALA48 3.5 29.5 1.0 C A:HIS50 3.5 34.6 1.0 C A:ILE53 3.6 34.3 1.0 C A:VAL56 3.7 34.9 1.0 CA A:ALA48 3.8 28.4 1.0 N A:HIS50 3.9 32.9 1.0 C A:LEU47 4.0 26.2 1.0 CB A:ILE53 4.1 34.5 1.0 CA A:ILE53 4.3 34.4 1.0 CA A:HIS50 4.3 34.0 1.0 N A:ALA48 4.3 26.5 1.0 N A:ALA49 4.4 30.7 1.0 N A:ILE53 4.4 35.4 1.0 CB A:VAL56 4.5 33.6 1.0 C A:ALA49 4.5 33.3 1.0 N A:ALA51 4.5 35.7 1.0 CA A:VAL56 4.6 34.4 1.0 N A:PRO57 4.6 36.2 1.0 N A:ALA58 4.7 38.0 1.0 CA A:PRO57 4.7 36.6 1.0 N A:LYS54 4.7 33.8 1.0 CG2 A:ILE53 4.7 33.5 1.0 C A:PRO57 4.7 37.2 1.0 CA A:ALA51 4.7 36.8 1.0 N A:VAL56 4.8 34.1 1.0 CB A:HIS50 4.9 33.1 1.0 CA A:LYS54 4.9 34.4 1.0 CA A:ALA49 4.9 32.1 1.0 C A:ALA51 4.9 37.1 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Phosphate-Bound Adenylosuccinate Lyase From E. Coli within 5.0Å range: probe atom residue distance (Å) B Occ A:Na502 b:14.0 occ:1.00 O A:SER331 2.4 23.2 1.0 O A:TRP333 2.9 20.4 1.0 O A:HOH808 3.2 42.4 1.0 O A:HOH617 3.6 18.7 1.0 C A:SER331 3.7 22.4 1.0 N A:TRP333 3.7 18.7 1.0 C A:TRP333 3.9 18.7 1.0 CA A:TRP333 4.1 18.5 1.0 C A:ARG332 4.2 20.0 1.0 O A:HOH859 4.4 30.6 1.0 N A:SER331 4.5 21.7 1.0 CA A:SER331 4.6 22.6 1.0 N A:ARG332 4.6 20.5 1.0 CA A:ARG332 4.6 19.9 1.0 CB A:SER331 4.8 23.9 1.0 O A:ARG332 4.8 18.6 1.0

G.Kozlov, L.Nguyen, J.Pearsall, K.Gehring. The Structure of Phosphate-Bound Escherichia Coli Adenylosuccinate Lyase Identifies HIS171 As A Catalytic Acid. Acta Crystallogr.,Sect.F V. 65 857 2009.
ISSN: ESSN 1744-3091
PubMed: 19724117
DOI: 10.1107/S1744309109029674