Atomistry » Sodium » PDB 3cq8-3dfh » 3d4l
Atomistry »
  Sodium »
    PDB 3cq8-3dfh »
      3d4l »

Sodium in PDB 3d4l: Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor

Enzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor

All present enzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor:
3.4.14.5;

Protein crystallography data

The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor, PDB code: 3d4l was solved by G.Scapin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.00
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 118.435, 125.749, 137.175, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 3d4l:

The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor also contains other interesting chemical elements:

Fluorine (F) 4 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor (pdb code 3d4l). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor, PDB code: 3d4l:

Sodium binding site 1 out of 1 in 3d4l

Go back to Sodium Binding Sites List in 3d4l
Sodium binding site 1 out of 1 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na1

b:35.2
occ:1.00
O A:GLY490 2.3 30.5 1.0
O A:LEU491 2.5 29.1 1.0
O A:HOH1765 2.6 31.8 1.0
C A:LEU491 3.2 28.4 1.0
C A:GLY490 3.5 29.5 1.0
CA A:LEU491 3.8 28.5 1.0
N A:ARG492 3.9 28.2 1.0
N A:LEU491 4.1 28.5 1.0
CA A:ARG492 4.2 28.6 1.0
CA A:GLY490 4.6 29.6 1.0

Reference:

G.B.Liang, X.Qian, T.Biftu, S.Singh, Y.D.Gao, G.Scapin, S.Patel, B.Leiting, R.Patel, J.Wu, X.Zhang, N.A.Thornberry, A.E.Weber. Discovery of New Binding Elements in Dpp-4 Inhibition and Their Applications in Novel Dpp-4 Inhibitor Design. Bioorg.Med.Chem.Lett. V. 18 3706 2008.
ISSN: ISSN 0960-894X
PubMed: 18524582
DOI: 10.1016/J.BMCL.2008.05.061
Page generated: Mon Oct 7 08:09:42 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy