Sodium in PDB 3cyx: Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira

All present enzymatic activity of Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira:
3.4.23.16;

The structure of Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira, PDB code: 3cyx was solved by F.Liu, I.T.Weber, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.20
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	58.900, 86.020, 46.390, 90.00, 90.00, 90.00
R / Rfree (%)	15 / 19.2

The binding sites of Sodium atom in the Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira (pdb code 3cyx). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira, PDB code: 3cyx:

Sodium binding site 1 out of 1 in the Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Hiv-1 Mutant I50V and Inhibitor Saquinavira within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:40.8 occ:1.00 O A:HOH1103 2.3 30.1 1.0 O A:HOH1078 2.4 25.8 1.0 O A:ASP60 2.5 12.4 1.0 O A:HOH1135 2.5 36.5 1.0 O A:HOH1235 2.5 30.1 0.5 O A:HOH1156 2.9 38.2 1.0 C A:ASP60 3.5 11.1 1.0 N A:ASP60 3.8 11.7 1.0 CA A:ASP60 4.0 11.2 1.0 O A:ARG41 4.3 16.1 1.0 CB A:ASP60 4.3 15.0 1.0 CB A:GLN61 4.4 19.7 1.0 N A:GLN61 4.5 12.1 1.0 O A:PRO39 4.6 19.3 1.0 CA A:GLY40 4.6 22.1 1.0 N A:ARG41 4.7 18.8 1.0 C A:TYR59 4.8 8.2 1.0 CA A:GLN61 4.8 13.5 1.0 O A:GLN61 4.9 16.0 1.0 C A:GLN61 4.9 12.6 1.0 CD1 A:ILE62 5.0 11.3 1.0

F.Liu, A.Y.Kovalevsky, Y.Tie, A.K.Ghosh, R.W.Harrison, I.T.Weber. Effect of Flap Mutations on Structure of Hiv-1 Protease and Inhibition By Saquinavir and Darunavir. J.Mol.Biol. V. 381 102 2008.
ISSN: ISSN 0022-2836
PubMed: 18597780
DOI: 10.1016/J.JMB.2008.05.062