Sodium in PDB 3cqx: Chaperone Complex

The structure of Chaperone Complex, PDB code: 3cqx was solved by Z.Xu, J.C.Nix, S.Misra, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.13 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.846, 105.808, 210.683, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 25.6

The binding sites of Sodium atom in the Chaperone Complex (pdb code 3cqx). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 4 binding sites of Sodium where determined in the Chaperone Complex, PDB code: 3cqx:
Jump to Sodium binding site number: 1; 2; 3; 4;

Sodium binding site 1 out of 4 in the Chaperone Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Chaperone Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:59.2 occ:1.00 N A:GLY75 2.8 39.3 1.0 OE2 A:GLU117 2.9 44.8 1.0 CA A:GLY75 3.6 40.3 1.0 NH2 A:ARG100 3.8 59.4 1.0 C A:ILE74 3.8 38.2 1.0 CG A:PRO116 3.8 39.9 1.0 CA A:ILE74 3.9 36.3 1.0 CB A:PRO116 3.9 40.1 1.0 CD A:PRO116 3.9 39.8 1.0 CD A:GLU117 4.0 45.7 1.0 O A:LEU73 4.2 35.3 1.0 CB A:ALA157 4.3 24.0 1.0 N A:ARG76 4.4 40.9 1.0 C A:GLY75 4.4 40.3 1.0 CG1 A:ILE74 4.5 36.0 1.0 N A:GLU117 4.6 38.6 1.0 OE1 A:GLU117 4.6 48.3 1.0 O A:ARG76 4.7 43.3 1.0 N A:PRO116 4.7 40.3 1.0 N A:ILE74 4.7 35.2 1.0 C A:LEU73 4.8 33.6 1.0 CB A:ILE74 4.8 36.0 1.0 CA A:PRO116 4.8 39.3 1.0 CZ A:ARG100 4.8 59.9 1.0 NE A:ARG100 5.0 58.5 1.0 O A:ILE74 5.0 39.2 1.0

Sodium binding site 2 out of 4 in the Chaperone Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Chaperone Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Na502 b:49.5 occ:1.00 O A:ILE74 2.8 39.2 1.0 OE1 A:GLN154 2.9 32.8 1.0 O A:LYS71 3.0 29.4 1.0 NE A:ARG76 3.2 38.8 1.0 O A:ARG72 3.6 30.1 1.0 CG2 A:ILE74 3.7 33.2 1.0 C A:ARG72 3.7 29.3 1.0 C A:ILE74 3.8 38.2 1.0 N A:ILE74 3.8 35.2 1.0 CD A:ARG76 3.8 38.1 1.0 CD A:GLN154 3.8 31.2 1.0 CG A:ARG76 3.8 41.0 1.0 CZ A:PHE150 3.9 25.5 1.0 CZ A:ARG76 3.9 37.8 1.0 C A:LEU73 4.0 33.6 1.0 CE2 A:PHE150 4.0 26.8 1.0 CG A:GLN154 4.0 28.4 1.0 C A:LYS71 4.1 29.6 1.0 NH2 A:ARG76 4.1 39.2 1.0 N A:LEU73 4.1 31.5 1.0 CA A:ILE74 4.2 36.3 1.0 CA A:ARG72 4.2 29.7 1.0 O A:LEU73 4.3 35.3 1.0 CA A:LEU73 4.4 32.9 1.0 CB A:ILE74 4.6 36.0 1.0 N A:ARG72 4.6 28.7 1.0 CE1 A:PHE150 4.7 25.6 1.0 CB A:GLN154 4.7 28.7 1.0 N A:GLY75 4.9 39.3 1.0 CD2 A:PHE150 4.9 26.1 1.0 NH1 A:ARG76 4.9 40.5 1.0 CB A:ARG76 5.0 39.8 1.0

Sodium binding site 3 out of 4 in the Chaperone Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Chaperone Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Na503 b:66.4 occ:1.00 O A:ILE130 2.9 41.3 1.0 O A:ALA30 2.9 38.8 1.0 CG2 A:ILE130 3.6 40.7 1.0 CB A:ALA133 3.6 44.2 1.0 C A:ILE130 3.8 41.6 1.0 CA A:ILE130 3.9 41.6 1.0 C A:ALA30 4.1 39.3 1.0 CG2 A:ILE29 4.1 35.7 1.0 CA A:ASN31 4.1 44.1 1.0 N A:TYR134 4.1 45.8 1.0 C A:ASN31 4.3 46.0 1.0 CB A:ILE130 4.3 42.1 1.0 CB A:TYR134 4.4 46.9 1.0 C A:ALA133 4.4 46.7 1.0 CA A:ALA133 4.5 46.3 1.0 N A:ASN31 4.6 40.9 1.0 O A:ASN31 4.7 46.6 1.0 CA A:TYR134 4.7 46.5 1.0 N A:ASP32 4.7 49.0 1.0 O A:HOH526 4.8 41.9 1.0 N A:ALA133 5.0 45.9 1.0 CG1 A:ILE130 5.0 42.4 1.0 N A:ALA131 5.0 41.6 1.0

Sodium binding site 4 out of 4 in the Chaperone Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Chaperone Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Na504 b:57.8 occ:1.00 OD2 A:ASP285 2.8 42.2 1.0 O D:HOH507 3.0 32.5 1.0 O D:GLN167 3.1 42.9 1.0 O D:CYS142 3.3 36.4 1.0 CB D:CYS142 3.5 36.4 1.0 C D:GLN167 3.6 43.3 1.0 CB D:LYS171 3.7 44.4 1.0 CG A:ASP285 3.7 41.5 1.0 CB D:GLN167 3.8 38.1 1.0 CB A:ASP285 3.8 39.9 1.0 CA D:CYS142 3.9 36.0 1.0 CD D:LYS171 4.0 46.7 1.0 C D:CYS142 4.0 35.5 1.0 CA D:GLN167 4.1 43.2 1.0 SG D:CYS142 4.3 40.3 1.0 O D:HOH505 4.3 40.8 1.0 CG1 D:VAL159 4.4 40.3 1.0 CG D:LYS171 4.4 45.6 1.0 NH2 A:ARG262 4.4 29.7 1.0 N D:LYS168 4.4 42.6 1.0 OE1 D:GLN167 4.5 31.4 1.0 CG D:GLN167 4.8 34.7 1.0 CA D:LYS168 4.8 43.9 1.0 CA D:LYS171 4.8 44.8 1.0 N D:LYS171 4.9 43.5 1.0 OD1 A:ASP285 4.9 40.9 1.0

Z.Xu, R.C.Page, M.M.Gomes, E.Kohli, J.C.Nix, A.B.Herr, C.Patterson, S.Misra. Structural Basis of Nucleotide Exchange and Client Binding By the HSP70 Cochaperone BAG2 Nat.Struct.Mol.Biol. V. 15 1309 2008.
ISSN: ISSN 1545-9993
PubMed: 19029896
DOI: 10.1038/NSMB.1518