Sodium in PDB 3cco: Structural Adaptation and Conservation in Quadruplex-Drug Recognition

The structure of Structural Adaptation and Conservation in Quadruplex-Drug Recognition, PDB code: 3cco was solved by G.N.Parkinson, S.Neidle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.20
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	61.350, 61.350, 43.630, 90.00, 90.00, 120.00
R / Rfree (%)	25.4 / 30.3

The structure of Structural Adaptation and Conservation in Quadruplex-Drug Recognition also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Sodium atom in the Structural Adaptation and Conservation in Quadruplex-Drug Recognition (pdb code 3cco). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structural Adaptation and Conservation in Quadruplex-Drug Recognition, PDB code: 3cco:

Sodium binding site 1 out of 1 in the Structural Adaptation and Conservation in Quadruplex-Drug Recognition


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structural Adaptation and Conservation in Quadruplex-Drug Recognition within 5.0Å range: probe atom residue distance (Å) B Occ A:Na4 b:14.5 occ:1.00 O A:HOH1020 2.0 19.3 1.0 O4' A:DG1011 2.8 22.6 1.0 C1' A:DG1011 3.5 18.9 1.0 C4' A:DG1011 3.7 25.2 1.0 N9 A:DG1011 4.3 15.2 1.0 O3' A:DG1011 4.6 35.0 1.0 C5' A:DG1011 4.6 25.9 1.0 N3 A:DG1010 4.7 11.1 1.0 N3 A:DG1011 4.7 10.9 1.0 C3' A:DG1011 4.7 26.7 1.0 C2' A:DG1011 4.8 21.4 1.0 C4 A:DG1011 4.8 9.6 1.0 C2' A:DG1010 4.8 18.4 1.0 N2 A:DG1010 5.0 16.0 1.0

G.N.Parkinson, F.Cuenca, S.Neidle. Topology Conservation and Loop Flexibility in Quadruplex-Drug Recognition: Crystal Structures of Inter- and Intramolecular Telomeric Dna Quadruplex-Drug Complexes J.Mol.Biol. V. 381 1145 2008.
ISSN: ISSN 0022-2836
PubMed: 18619463
DOI: 10.1016/J.JMB.2008.06.022