Sodium in PDB 3b5g: Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2

The structure of Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2, PDB code: 3b5g was solved by A.Hernandez-Santoyo, A.Rodriguez-Romero, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.34 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.770, 68.590, 83.850, 90.00, 90.00, 90.00
R / Rfree (%)	16.4 / 21

The binding sites of Sodium atom in the Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2 (pdb code 3b5g). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2, PDB code: 3b5g:

Sodium binding site 1 out of 1 in the Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na601 b:16.5 occ:1.00 O A:HOH247 2.6 26.9 1.0 O A:ASN53 2.7 10.6 1.0 N A:GLY65 3.0 13.2 1.0 OXT A:ACT402 3.2 42.7 1.0 CA A:SER64 3.3 15.0 1.0 NH1 A:ARG55 3.4 17.3 1.0 C A:ASN53 3.5 9.6 1.0 CB A:SER64 3.5 17.4 1.0 CB A:ASN53 3.6 9.5 1.0 C A:SER64 3.6 13.5 1.0 CA A:ASN53 3.7 10.7 1.0 O A:GLY65 3.7 10.9 1.0 CD1 A:ILE49 3.8 9.2 1.0 CA A:GLY65 4.1 11.6 1.0 O A:PHE63 4.2 15.0 1.0 C A:GLY65 4.4 11.9 1.0 C A:ACT402 4.4 41.8 1.0 CZ A:ARG55 4.5 17.3 1.0 N A:SER64 4.5 13.6 1.0 N A:GLN54 4.7 9.5 1.0 CG A:ASN53 4.8 11.7 1.0 C A:PHE63 4.8 13.8 1.0 OG A:SER64 4.8 18.9 1.0 O A:ACT402 4.8 41.3 1.0 O A:SER64 4.9 13.0 1.0 CG A:ARG55 5.0 12.7 1.0

A.Hernandez-Santoyo, L.Del Pozo Yauner, D.Fuentes-Silva, E.Ortiz, E.Rudino-Pinera, R.Sanchez-Lopez, E.Horjales, B.Becerril, A.Rodriguez-Romero. A Single Mutation at the Sheet Switch Region Results in Conformational Changes Favoring LAMBDA6 Light-Chain Fibrillogenesis. J.Mol.Biol. V. 396 280 2010.
ISSN: ISSN 0022-2836
PubMed: 19941869
DOI: 10.1016/J.JMB.2009.11.038