Sodium in PDB 2r0w: PFA2 Fab Complexed with ABETA1-8

The structure of PFA2 Fab Complexed with ABETA1-8, PDB code: 2r0w was solved by A.S.Gardberg, C.Dealwis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.64 / 2.50
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	42.793, 43.327, 58.456, 92.51, 94.96, 90.55
R / Rfree (%)	20.8 / 27.7

The binding sites of Sodium atom in the PFA2 Fab Complexed with ABETA1-8 (pdb code 2r0w). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the PFA2 Fab Complexed with ABETA1-8, PDB code: 2r0w:

Sodium binding site 1 out of 1 in the PFA2 Fab Complexed with ABETA1-8


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of PFA2 Fab Complexed with ABETA1-8 within 5.0Å range: probe atom residue distance (Å) B Occ L:Na214 b:50.3 occ:1.00 OD1 L:ASP82 3.6 39.8 1.0 CE2 L:PHE62 3.9 41.7 1.0 CZ L:PHE62 4.1 40.4 1.0 CD L:GLU81 4.1 52.6 1.0 CG L:GLU81 4.1 46.9 1.0 OE2 L:GLU81 4.3 52.5 1.0 CD2 L:LEU37 4.3 37.2 1.0 O L:GLU81 4.3 42.0 1.0 NH2 L:ARG61 4.5 41.0 1.0 C L:GLU81 4.6 41.8 1.0 OE1 L:GLU81 4.6 55.4 1.0 CA L:ASP82 4.6 39.9 1.0 NZ L:LYS45 4.7 49.3 1.0 N L:ASP82 4.7 40.5 1.0 CG L:ASP82 4.7 39.6 1.0 CB L:GLU81 4.8 43.0 1.0 CD L:PRO59 4.8 43.8 1.0 CG L:PRO59 5.0 44.5 1.0

A.S.Gardberg, L.T.Dice, S.Ou, R.L.Rich, E.Helmbrecht, J.Ko, R.Wetzel, D.G.Myszka, P.H.Patterson, C.Dealwis. Molecular Basis For Passive Immunotherapy of Alzheimer'S Disease Proc.Natl.Acad.Sci.Usa V. 104 15659 2007.
ISSN: ISSN 0027-8424
PubMed: 17895381
DOI: 10.1073/PNAS.0705888104