Sodium in PDB 2qr8: 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2)

All present enzymatic activity of 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2):
2.7.11.1;

The structure of 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2), PDB code: 2qr8 was solved by V.Tereshko, M.Malakhova, Z.Dong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	46.912, 46.912, 291.076, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 25.9

The binding sites of Sodium atom in the 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2) (pdb code 2qr8). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2), PDB code: 2qr8:

Sodium binding site 1 out of 1 in the 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of 2.0A X-Ray Structure of C-Terminal Kinase Domain of P90 Ribosomal S6 Kinase 2 (RSK2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1000 b:48.0 occ:1.00 O A:HIS473 2.2 48.4 1.0 O A:GLY471 2.3 53.3 1.0 O A:HOH1001 2.3 49.7 1.0 O A:ILE476 2.4 51.7 1.0 OG1 A:THR478 2.5 54.2 1.0 O A:HOH1002 2.8 72.0 1.0 C A:HIS473 3.4 48.7 1.0 C A:GLY471 3.4 53.1 1.0 C A:ILE476 3.5 51.9 1.0 CB A:THR478 3.6 54.7 1.0 N A:THR478 3.7 54.5 1.0 CA A:THR478 3.8 55.0 1.0 C A:ILE477 3.9 54.2 1.0 C A:GLN472 4.0 51.0 1.0 CG2 A:THR478 4.0 53.8 1.0 N A:HIS473 4.0 50.3 1.0 N A:ILE476 4.0 49.4 1.0 N A:PRO474 4.2 47.5 1.0 O A:ILE477 4.2 54.2 1.0 C A:PRO474 4.2 48.6 1.0 CA A:PRO474 4.2 48.1 1.0 OE2 A:GLU494 4.3 56.4 1.0 CA A:ILE476 4.3 50.3 1.0 CA A:HIS473 4.3 49.0 1.0 N A:GLN472 4.3 52.9 1.0 CA A:GLN472 4.3 52.5 1.0 O A:GLN472 4.3 50.5 1.0 CA A:GLY471 4.3 53.9 1.0 O A:PRO474 4.4 50.1 1.0 N A:ILE477 4.5 52.9 1.0 CB A:ILE476 4.5 50.5 1.0 CA A:ILE477 4.5 53.1 1.0 N A:ASN475 4.6 48.5 1.0 NE A:ARG558 4.8 43.7 1.0 CD A:ARG558 5.0 43.8 1.0 CB A:HIS473 5.0 48.9 1.0

M.Malakhova, V.Tereshko, S.Y.Lee, K.Yao, Y.-Y.Cho, A.Bode, Z.Dong. Structural Basis For Activation of the Autoinhibitory C-Terminal Kinase Domain of P90 RSK2. Nat.Struct.Mol.Biol. V. 15 112 2008.
ISSN: ISSN 1545-9993
PubMed: 18084304
DOI: 10.1038/NSMB1347