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Atomistry » Sodium » PDB 2ok7-2ozt » 2oph | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 2ok7-2ozt » 2oph » |
Sodium in PDB 2oph: Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid InhibitorEnzymatic activity of Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor
All present enzymatic activity of Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor:
3.4.14.5; Protein crystallography data
The structure of Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor, PDB code: 2oph
was solved by
G.Scapin,
A.E.Weber,
J.L.Duffy,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2oph:
The structure of Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor
(pdb code 2oph). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor, PDB code: 2oph: Sodium binding site 1 out of 1 in 2ophGo back to![]() ![]()
Sodium binding site 1 out
of 1 in the Human Dipeptidyl Peptidase IV in Complex with An Alpha Amino Acid Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.L.Duffy,
B.A.Kirk,
L.Wang,
G.J.Eiermann,
H.He,
B.Leiting,
K.A.Lyons,
R.A.Patel,
S.B.Patel,
A.Petrov,
G.Scapin,
J.K.Wu,
N.A.Thornberry,
A.E.Weber.
4-Aminophenylalanine and 4-Aminocyclohexylalanine Derivatives As Potent, Selective, and Orally Bioavailable Inhibitors of Dipeptidyl Peptidase IV. Bioorg.Med.Chem.Lett. V. 17 2879 2007.
Page generated: Tue Dec 15 05:52:44 2020
ISSN: ISSN 0960-894X PubMed: 17350841 DOI: 10.1016/J.BMCL.2007.02.066 |
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