Sodium in PDB 2g7b: Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution

The structure of Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution, PDB code: 2g7b was solved by S.Vaezeslami, J.H.Geiger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.81 / 1.18
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.459, 45.514, 77.747, 90.00, 90.00, 90.00
R / Rfree (%)	12.9 / 15.5

The binding sites of Sodium atom in the Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution (pdb code 2g7b). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution, PDB code: 2g7b:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na300 b:34.8 occ:1.00 O A:HOH512 2.0 24.5 0.5 O A:HOH454 2.5 42.5 1.0 OD2 A:ASP48 2.8 14.1 1.0 O A:HOH512 2.9 19.8 0.5 O A:HOH484 3.2 34.2 1.0 CG A:ASP48 3.6 12.0 1.0 O A:GLY47 3.8 15.1 1.0 CZ2 A:TRP87 3.9 10.7 1.0 C A:GLY47 3.9 13.2 1.0 O A:HOH543 4.0 48.2 1.0 OD1 A:ASP48 4.0 16.7 1.0 NE2 A:GLN45 4.1 16.8 1.0 NE1 A:TRP87 4.2 10.8 1.0 O A:HOH326 4.3 11.8 0.3 N A:ASP48 4.3 12.0 1.0 O A:HOH538 4.3 31.3 1.0 CE2 A:TRP87 4.3 10.1 1.0 CD A:PRO1 4.4 19.8 1.0 CA A:ASP48 4.5 10.9 1.0 CA A:GLY47 4.5 15.2 1.0 CB A:ASP48 4.6 11.4 1.0 O A:HOH326 4.7 9.9 0.4 CG A:PRO1 4.8 18.1 1.0 CH2 A:TRP87 4.9 11.0 1.0 O A:HOH438 4.9 33.8 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the R132K:R111L:L121E Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinal at 1.18 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:42.5 occ:1.00 O A:HOH550 2.1 38.5 1.0 O A:HOH515 2.5 17.1 0.5 O A:GLY68 3.0 13.9 1.0 C A:GLY68 3.5 11.6 1.0 CA A:GLY68 3.6 11.6 1.0 O A:HOH330 3.9 21.2 1.0 O A:VAL67 4.4 11.6 1.0 N A:GLU69 4.6 11.1 1.0 CG A:GLU69 4.6 14.8 1.0 O A:HOH480 4.7 18.7 0.5 N A:GLY68 4.8 10.3 1.0 O A:HOH551 5.0 46.8 1.0

C.Vasileiou, S.Vaezeslami, R.M.Crist, M.Rabago-Smith, J.H.Geiger, B.Borhan. Protein Design: Reengineering Cellular Retinoic Acid Binding Protein II Into A Rhodopsin Protein Mimic. J.Am.Chem.Soc. V. 129 6140 2007.
ISSN: ISSN 0002-7863
PubMed: 17447762
DOI: 10.1021/JA067546R