Sodium in PDB 2c9a: Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu

All present enzymatic activity of Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu:
3.1.3.48;

The structure of Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu, PDB code: 2c9a was solved by A.R.Aricescu, W.C.Hon, C.Siebold, W.Lu, P.A.Van Der Merwe, E.Y.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.70
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	58.856, 97.737, 134.357, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 27.5

The binding sites of Sodium atom in the Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu (pdb code 2c9a). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu, PDB code: 2c9a:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1288 b:33.6 occ:1.00 OD1 A:ASN47 2.6 46.3 1.0 O A:PHE46 2.6 43.7 1.0 O A:SER41 2.8 49.7 1.0 OD1 A:ASP44 3.1 43.0 1.0 OE1 A:GLN40 3.2 45.9 1.0 N A:SER41 3.2 48.0 1.0 OD2 A:ASP44 3.2 43.2 1.0 CG A:ASP44 3.5 43.2 1.0 C A:SER41 3.6 49.3 1.0 CG A:ASN47 3.6 44.8 1.0 O A:HIS83 3.7 43.6 1.0 C A:PHE46 3.7 43.3 1.0 CA A:SER41 3.8 48.8 1.0 N A:HIS83 3.8 41.4 1.0 CA A:ASN47 3.8 41.8 1.0 CB A:GLN40 3.8 46.3 1.0 CB A:SER41 4.1 49.0 1.0 C A:GLN40 4.2 47.1 1.0 CD A:GLN40 4.2 45.8 1.0 N A:ASN47 4.2 42.8 1.0 CB A:ASN47 4.3 42.1 1.0 O A:HOH2008 4.3 30.6 1.0 CA A:GLN40 4.3 46.5 1.0 CA A:ALA82 4.5 41.9 1.0 C A:HIS83 4.6 42.1 1.0 C A:ALA82 4.6 41.4 1.0 CG A:GLN40 4.6 46.1 1.0 CA A:HIS83 4.6 42.3 1.0 ND2 A:ASN47 4.7 45.5 1.0 CB A:ALA82 4.7 42.2 1.0 OG A:SER41 4.9 49.0 1.0 N A:GLU42 4.9 49.0 1.0 C A:ASN47 4.9 40.9 1.0 N A:TRP48 5.0 40.1 1.0 CA A:PHE46 5.0 42.9 1.0 CB A:HIS83 5.0 42.0 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the Mam-Ig Module of Receptor Protein Tyrosine Phosphatase Mu within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1289 b:44.5 occ:1.00 O A:ASP173 2.3 44.7 1.0 OG A:SER67 2.3 48.7 1.0 O A:LEU28 2.4 43.7 1.0 O A:SER67 2.6 49.0 1.0 C A:SER67 3.5 48.9 1.0 C A:ASP173 3.5 44.6 1.0 C A:LEU28 3.6 43.6 1.0 CB A:SER67 3.6 48.8 1.0 CA A:SER67 4.0 48.9 1.0 N A:SER67 4.1 49.1 1.0 CB A:ASP173 4.1 44.9 1.0 CA A:ASP173 4.1 44.5 1.0 CA A:LEU28 4.2 43.8 1.0 OD1 A:ASP30 4.5 47.4 1.0 N A:PHE68 4.5 48.8 1.0 CG A:ASP173 4.6 46.9 1.0 CB A:GLU174 4.6 45.1 1.0 N A:GLU174 4.6 44.7 1.0 CB A:LEU28 4.6 44.1 1.0 OD2 A:ASP173 4.6 50.4 1.0 CB A:PHE29 4.7 40.9 1.0 N A:PHE29 4.7 42.7 1.0 CD2 A:PHE29 4.7 37.8 1.0 CA A:GLU174 4.9 44.8 1.0 CA A:PHE68 5.0 48.9 1.0 CA A:PHE29 5.0 41.7 1.0

A.R.Aricescu, W.C.Hon, C.Siebold, W.Lu, P.A.Van Der Merwe, E.Y.Jones. Molecular Analysis of Receptor Protein Tyrosine Phosphatase Mu-Mediated Cell Adhesion. Embo J. V. 25 701 2006.
ISSN: ISSN 0261-4189
PubMed: 16456543
DOI: 10.1038/SJ.EMBOJ.7600974