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Atomistry » Sodium » PDB 5hn3-5i9b » 5i7u | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 5hn3-5i9b » 5i7u » |
Sodium in PDB 5i7u: Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle InhibitorEnzymatic activity of Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor
All present enzymatic activity of Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor:
3.4.14.5; Protein crystallography data
The structure of Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor, PDB code: 5i7u
was solved by
G.Scapin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5i7u:
The structure of Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor
(pdb code 5i7u). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor, PDB code: 5i7u: Sodium binding site 1 out of 1 in 5i7uGo back to![]() ![]()
Sodium binding site 1 out
of 1 in the Human DPP4 in Complex with A Novel Tricyclic Hetero-Cycle Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
W.L.Wu,
J.Hao,
M.Domalski,
D.A.Burnett,
D.Pissarnitski,
Z.Zhao,
A.Stamford,
G.Scapin,
Y.D.Gao,
A.Soriano,
T.M.Kelly,
Z.Yao,
M.A.Powles,
S.Chen,
H.Mei,
J.Hwa.
Discovery of Novel Tricyclic Heterocycles As Potent and Selective Dpp-4 Inhibitors For the Treatment of Type 2 Diabetes. Acs Med.Chem.Lett. V. 7 498 2016.
Page generated: Mon Oct 7 21:32:41 2024
ISSN: ISSN 1948-5875 PubMed: 27190600 DOI: 10.1021/ACSMEDCHEMLETT.6B00027 |
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