Sodium in the structure of Thrombin Inhibitors (pdb 2c8w)

The binding sites of Sodium atom in the structure of Thrombin Inhibitors (pdb code 2c8w). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2c8w structure was solved by N.HOWARD, C.ABELL, W.BLAKEMORE, R.CARR, G.CHESSARI, M.CONGREVE, S.HOWARD, H.JHOTI, C.W.MURRAY, L.C.A.SEAVERS, R.L.M.VAN MONTFORT, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 70.7-2.0 Space group C121 a (A) 70.579 b (A) 71.906 c (A) 72.200 alpha (°) 90.00 beta (°) 100.42 gamma (°) 90.00 Rfactor (%) 16.4 Rfree (%) 21.9 Sodium Binding Sites: Sodium binding site 1 out of 1 in 2c8w Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2c8w. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Tyr184, B: Asp221, B: Arg221A, B: Asp222, B: Gly223, B: Lys224, B: Tyr225, B: Hoh2277, B: Hoh2279, B: Hoh2293, B: Hoh2294, B: Hoh2295, B: Hoh2314, B: Hoh2318, B: Hoh2328, conact list: Atom Atom Distance (A) Na O B:Tyr184 3.99 Na O B:Asp221 4.74 Na C B:Asp221 4.16 Na OD1 B:Asp221 4.71 Na CA B:Asp221 4.41 Na O B:Arg221A 2.27 Na N B:Arg221A 3.92 Na C B:Arg221A 3.37 Na CA B:Arg221A 4.26 Na N B:Asp222 4.24 Na C B:Asp222 4.55 Na CA B:Asp222 4.34 Na N B:Gly223 4.39 Na C B:Gly223 4.93 Na O B:Lys224 2.29 Na N B:Lys224 3.84 Na CB B:Lys224 4.45 Na C B:Lys224 3.40 Na CA B:Lys224 4.11 Na N B:Tyr225 4.42 Na CD1 B:Tyr225 4.93 Na CA B:Tyr225 4.71 Na O B:Hoh2277 2.46 Na O B:Hoh2279 2.68 Na O B:Hoh2293 3.93 Na O B:Hoh2294 4.17 Na O B:Hoh2295 2.37 Na O B:Hoh2314 4.97 Na O B:Hoh2318 2.40 Na O B:Hoh2328 3.93 interactive model: