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Sodium in PDB 1o2g: Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors

Enzymatic activity of Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors

All present enzymatic activity of Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors:
3.4.21.5;

Protein crystallography data

The structure of Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors, PDB code: 1o2g was solved by B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, W.F.Tai, H.Hui, G.Breitenbucher, D.Allen, J.Janc, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 7.00 / 1.58
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 71.360, 72.060, 72.960, 90.00, 101.77, 90.00
R / Rfree (%) 21.9 / 25

Sodium Binding Sites:

The binding sites of Sodium atom in the Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors (pdb code 1o2g). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors, PDB code: 1o2g:

Sodium binding site 1 out of 1 in 1o2g

Go back to Sodium Binding Sites List in 1o2g
Sodium binding site 1 out of 1 in the Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Na409

b:29.9
occ:1.00
O H:ARG221A 2.4 27.7 1.0
O H:LYS224 2.5 22.3 1.0
O H:HOH452 2.5 32.4 1.0
O H:HOH454 2.6 27.3 1.0
O H:HOH428 2.6 22.6 1.0
O H:HOH431 2.7 25.3 1.0
H1 H:HOH428 2.8 25.6 1.0
H2 H:HOH452 2.9 32.8 1.0
H H:LYS224 3.0 27.2 1.0
H2 H:HOH431 3.0 24.5 1.0
H1 H:HOH454 3.1 26.2 1.0
H2 H:HOH428 3.1 20.9 1.0
H1 H:HOH431 3.1 25.9 1.0
H1 H:HOH452 3.2 34.9 1.0
HA H:ASP222 3.3 31.8 1.0
H2 H:HOH454 3.3 27.2 1.0
H2 H:HOH439 3.4 20.4 1.0
C H:ARG221A 3.5 28.9 1.0
C H:LYS224 3.5 21.2 1.0
H1 H:HOH422 3.6 29.4 1.0
H H:GLY223 3.6 30.1 1.0
HA H:ASP221 3.6 28.4 1.0
N H:LYS224 3.8 25.5 1.0
HB2 H:LYS224 3.9 28.1 1.0
HA H:TYR225 3.9 19.6 1.0
O H:HOH439 4.0 20.7 1.0
O H:HOH441 4.0 28.9 1.0
N H:ARG221A 4.0 27.2 1.0
H H:ARG221A 4.1 25.6 1.0
N H:GLY223 4.1 30.5 1.0
C H:ASP221 4.1 26.9 1.0
CA H:ASP222 4.1 31.7 1.0
O H:TYR184A 4.2 24.7 1.0
CA H:LYS224 4.2 23.1 1.0
N H:ASP222 4.2 28.9 1.0
O H:HOH422 4.4 24.9 1.0
C H:ASP222 4.4 32.9 1.0
CA H:ASP221 4.4 29.0 1.0
H1 H:HOH439 4.4 20.9 1.0
CA H:ARG221A 4.4 27.6 1.0
O H:ASP221 4.5 26.5 1.0
N H:TYR225 4.5 18.6 1.0
CB H:LYS224 4.6 26.6 1.0
H2 H:HOH422 4.7 26.4 1.0
H1 H:HOH441 4.7 27.3 1.0
H2 H:HOH441 4.7 28.9 1.0
H1 H:HOH435 4.7 36.7 1.0
OD1 H:ASP221 4.7 30.2 1.0
CA H:TYR225 4.7 19.4 1.0
C H:GLY223 4.8 29.0 1.0
O H:HOH435 4.8 34.6 1.0
HB2 H:ARG221A 4.9 29.9 1.0
HA3 H:GLY184 4.9 20.1 1.0
HB2 H:ASP189 4.9 22.6 1.0
CD1 H:TYR225 5.0 18.6 1.0
H H:TYR184A 5.0 20.6 1.0
HD1 H:TYR225 5.0 18.8 1.0

Reference:

B.A.Katz, K.Elrod, E.Verner, R.L.Mackman, C.Luong, W.D.Shrader, M.Sendzik, J.R.Spencer, P.A.Sprengeler, A.Kolesnikov, V.W.-F.Tai, H.C.Hui, J.G.Breitenbucher, D.Allen, J.W.Janc. Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors J.Mol.Biol. V. 329 93 2003.
ISSN: ISSN 0022-2836
PubMed: 12742021
DOI: 10.1016/S0022-2836(03)00399-1
Page generated: Sun Oct 6 21:07:55 2024

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