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PDB 1ghy-1hn1 »
1gj4 »
Sodium in PDB 1gj4: Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design
Enzymatic activity of Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design
All present enzymatic activity of Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design, PDB code: 1gj4
was solved by
B.A.Katz,
P.A.Sprengeler,
C.Luong,
E.Verner,
J.R.Spencer,
J.G.Breitenbucher,
H.Hui,
D.Mcgee,
D.Allen,
A.Martelli,
R.L.Mackman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 7.00 / 1.81 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 71.370, 72.090, 72.840, 90.00, 100.97, 90.00 |
| R / Rfree (%) | 20.2 / 23.6 |
Other elements in 1gj4:
The structure of Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
Sodium Binding Sites:
The binding sites of Sodium atom in the Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design
(pdb code 1gj4). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design, PDB code: 1gj4:
In total only one binding site of Sodium was determined in the Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design, PDB code: 1gj4:
Sodium binding site 1 out of 1 in 1gj4
Go back to
Sodium Binding Sites List in 1gj4
Sodium binding site 1 out
of 1 in the Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Selectivity at S1, H2O Displacement, Upa, Tpa, SER190/ALA190 Protease, Structure-Based Drug Design within 5.0Å range:
|
Reference:
B.A.Katz,
P.A.Sprengeler,
C.Luong,
E.Verner,
K.Elrod,
M.Kirtley,
J.Janc,
J.R.Spencer,
J.G.Breitenbucher,
H.Hui,
D.Mcgee,
D.Allen,
A.Martelli,
R.L.Mackman.
Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets. Chem.Biol. V. 8 1107 2001.
ISSN: ISSN 1074-5521
PubMed: 11731301
DOI: 10.1016/S1074-5521(01)00084-9
Page generated: Sun Oct 6 18:37:04 2024
ISSN: ISSN 1074-5521
PubMed: 11731301
DOI: 10.1016/S1074-5521(01)00084-9
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