Sodium in PDB 1d12: Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin

The structure of Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin, PDB code: 1d12 was solved by C.A.Frederick, L.D.Williams, G.Ughetto, G.A.Van Der Marel, J.H.Van Boom, A.Rich, A.H.-J.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.70
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	28.210, 28.210, 53.190, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Sodium atom in the Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin (pdb code 1d12). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin, PDB code: 1d12:

Sodium binding site 1 out of 1 in the Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structural Comparison of Anticancer Drug-Dna Complexes. Adriamycin and Daunomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Na9 b:35.3 occ:1.00 N7 A:DG6 2.8 6.6 1.0 O A:HOH11 2.8 38.1 1.0 O6 A:DM27 3.0 8.9 1.0 O4 A:DM27 3.1 7.9 1.0 O A:HOH10 3.1 35.5 1.0 O A:HOH12 3.1 36.3 1.0 C21 A:DM27 3.5 7.8 1.0 C8 A:DG6 3.7 5.9 1.0 C5 A:DG6 3.8 5.7 1.0 O6 A:DG6 3.8 5.1 1.0 C4 A:DM27 3.9 7.3 1.0 C6 A:DM27 3.9 7.2 1.0 C6 A:DG6 4.2 5.0 1.0 C5 A:DM27 4.2 7.5 1.0 C2' A:DC5 4.3 12.1 1.0 O A:HOH45 4.5 34.4 1.0 O A:HOH60 4.6 33.9 1.0 O8 A:DM27 4.7 8.1 1.0 O3' A:DC5 4.8 15.0 1.0 O A:HOH49 4.8 36.3 1.0 N9 A:DG6 4.9 6.0 1.0 OP2 A:DG6 4.9 16.1 1.0 C7 A:DM27 4.9 7.3 1.0 C4 A:DG6 4.9 5.5 1.0 C3 A:DM27 4.9 8.5 1.0

C.A.Frederick, L.D.Williams, G.Ughetto, G.A.Van Der Marel, J.H.Van Boom, A.Rich, A.H.Wang. Structural Comparison of Anticancer Drug-Dna Complexes: Adriamycin and Daunomycin. Biochemistry V. 29 2538 1990.
ISSN: ISSN 0006-2960
PubMed: 2334681
DOI: 10.1021/BI00462A016