Sodium in PDB 8cod: Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine

All present enzymatic activity of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine:
3.13.2.1;

The structure of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine, PDB code: 8cod was solved by R.Saleem-Batcha, D.Popadic, L.H.Koeppl, J.N.Andexer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	88.25 / 2.48
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	98.22, 102.526, 173.408, 90, 90, 90
R / Rfree (%)	14.6 / 21.6

The binding sites of Sodium atom in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine (pdb code 8cod). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine, PDB code: 8cod:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine within 5.0Å range: probe atom residue distance (Å) B Occ A:Na603 b:58.2 occ:1.00 O A:HIS353 2.7 29.4 1.0 O A:HOH809 2.8 50.4 1.0 O A:MET351 2.9 36.7 1.0 OE2 A:GLU59 3.0 38.4 1.0 OE1 A:GLU59 3.1 36.4 1.0 O A:HOH813 3.2 34.9 1.0 CD A:GLU59 3.2 35.4 1.0 O B:HOH706 3.3 46.0 1.0 C A:HIS353 3.7 30.5 1.0 CA A:PRO354 3.8 29.4 1.0 C A:MET351 3.9 30.2 1.0 CB A:MET351 4.0 33.1 1.0 O A:GLY352 4.0 28.7 1.0 N A:PRO354 4.1 31.3 1.0 O6 A:NOS602 4.1 40.1 1.0 CB B:ASP208 4.2 32.8 1.0 O B:HOH827 4.3 42.0 1.0 C A:PRO354 4.3 29.2 1.0 C A:GLY352 4.4 30.7 1.0 CG A:GLU59 4.4 32.1 1.0 N A:SER355 4.4 32.2 1.0 CG B:ASP208 4.5 41.2 1.0 CA A:MET351 4.6 31.6 1.0 O B:ASP208 4.7 34.9 1.0 N A:HIS353 4.8 30.3 1.0 N A:GLY352 4.8 30.1 1.0 CA A:HIS353 4.9 28.7 1.0 OD1 B:ASP208 4.9 43.5 1.0 CA A:GLY352 4.9 31.6 1.0 OD2 B:ASP208 5.0 34.2 1.0 NE2 A:GLN85 5.0 33.3 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine within 5.0Å range: probe atom residue distance (Å) B Occ B:Na603 b:59.7 occ:1.00 O B:HOH799 2.6 45.3 1.0 O B:HOH733 2.8 37.5 1.0 OE1 B:GLU59 2.9 47.5 1.0 O B:MET351 2.9 31.9 1.0 O B:HIS353 2.9 33.7 1.0 OE2 B:GLU59 3.3 51.0 1.0 CD B:GLU59 3.3 48.1 1.0 CB B:MET351 3.6 31.0 1.0 C B:MET351 3.8 33.7 1.0 C B:HIS353 3.8 35.1 1.0 O A:HOH711 3.9 37.4 1.0 CA B:PRO354 3.9 33.4 1.0 O B:GLY352 4.0 27.1 1.0 O6 B:NOS602 4.1 49.3 1.0 CB A:ASP208 4.1 33.4 1.0 N B:PRO354 4.2 33.6 1.0 CG A:ASP208 4.3 38.6 1.0 CA B:MET351 4.3 33.1 1.0 C B:GLY352 4.4 27.2 1.0 C B:PRO354 4.5 33.6 1.0 OD1 A:ASP208 4.5 39.2 1.0 NE2 B:GLN85 4.6 41.9 1.0 CG B:GLU59 4.6 41.7 1.0 O A:ASP208 4.6 39.0 1.0 OD2 A:ASP208 4.7 39.0 1.0 N B:SER355 4.7 32.7 1.0 N B:GLY352 4.8 32.8 1.0 CG B:MET351 4.9 34.7 1.0 N B:HIS353 4.9 27.2 1.0

R.Saleem-Batcha, D.Popadic, L.H.Koeppl, J.N.Andexer. Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From Mus Musculus in Complex with Inosine To Be Published.