Sodium in PDB 7pqs: SRPK1 in Complex with MSC2711186

All present enzymatic activity of SRPK1 in Complex with MSC2711186:
2.7.11.1;

The structure of SRPK1 in Complex with MSC2711186, PDB code: 7pqs was solved by M.Schroeder, M.Leiendecker, S.Knapp, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.86 / 2.20
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	75.132, 75.132, 309.709, 90, 90, 120
R / Rfree (%)	19.9 / 23.6

The structure of SRPK1 in Complex with MSC2711186 also contains other interesting chemical elements:

Fluorine	(F)	2 atoms
Chlorine	(Cl)	4 atoms

The binding sites of Sodium atom in the SRPK1 in Complex with MSC2711186 (pdb code 7pqs). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the SRPK1 in Complex with MSC2711186, PDB code: 7pqs:

Sodium binding site 1 out of 1 in the SRPK1 in Complex with MSC2711186


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of SRPK1 in Complex with MSC2711186 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na507 b:57.7 occ:1.00 OE1 B:GLU429 3.3 47.2 1.0 O B:ARG424 3.4 35.4 1.0 OE2 B:GLU429 3.5 52.5 1.0 CD B:GLU429 3.8 47.1 1.0 O B:GLU422 3.8 48.1 1.0 C B:ARG424 4.3 33.8 1.0 O B:LYS423 4.3 37.4 1.0 C B:LYS423 4.4 41.2 1.0 O B:HOH631 4.4 33.7 1.0 CG2 B:THR426 4.6 35.2 1.0 CA B:LYS423 4.7 43.8 1.0 N B:ARG424 4.8 37.3 1.0 C B:GLU422 4.8 44.6 1.0 CA B:ALA425 4.8 32.1 1.0 N B:ALA425 4.8 31.6 1.0 N B:THR426 4.9 33.2 1.0

M.Schroeder, M.Leiendecker, S.Knapp. SRPK1 in Complex with MSC2711186 To Be Published.