Atomistry » Sodium » PDB 6sfo-6sxg » 6sgp
Atomistry »
  Sodium »
    PDB 6sfo-6sxg »
      6sgp »

Sodium in PDB 6sgp: X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu

Enzymatic activity of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu

All present enzymatic activity of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu:
3.4.17.21;

Protein crystallography data

The structure of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu, PDB code: 6sgp was solved by C.Barinka, S.Shukla, L.Motlova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.90 / 1.58
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 101.349, 130.394, 158.538, 90.00, 90.00, 90.00
R / Rfree (%) 18 / 20.1

Other elements in 6sgp:

The structure of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu also contains other interesting chemical elements:

Zinc (Zn) 2 atoms
Calcium (Ca) 1 atom
Chlorine (Cl) 1 atom

Sodium Binding Sites:

The binding sites of Sodium atom in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu (pdb code 6sgp). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu, PDB code: 6sgp:

Sodium binding site 1 out of 1 in 6sgp

Go back to Sodium Binding Sites List in 6sgp
Sodium binding site 1 out of 1 in the X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na827

b:51.4
occ:1.00
 O A:HOH1295 2.3 37.4 1.0
OE1 A:GLU437 2.3 42.0 1.0
ND2 A:ASN275 2.8 27.5 1.0
O A:HOH1301 3.0 40.9 1.0
O A:HOH921 3.0 36.2 1.0
O A:HOH912 3.2 47.1 1.0
CD A:GLU437 3.3 31.6 1.0
CG A:PRO273 3.6 20.7 1.0
CB A:ASN275 3.7 24.1 1.0
CG A:GLU437 3.7 24.7 1.0
CG A:ASN275 3.7 23.9 1.0
CB A:PRO273 4.3 19.6 1.0
OH A:TYR277 4.3 30.5 1.0
OE2 A:GLU437 4.4 31.1 1.0
O A:HOH1209 4.7 24.3 1.0
CB A:GLU437 4.7 21.1 1.0
OD1 A:ASN275 4.9 24.4 1.0
CZ A:TYR277 4.9 28.4 1.0
CE2 A:TYR277 5.0 28.9 1.0

Reference:

C.Barinka, S.Shukla, L.Motlova. X-Ray Structure of Human Glutamate Carboxypeptidase II (Gcpii) - the E424M Inactive Mutant, in Complex with A Sulfamide Inhibitor Gluglu To Be Published.
Page generated: Tue Oct 8 13:28:27 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy