Sodium in PDB 6p9m: Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J

All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J:
2.3.1.41;

The structure of Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J, PDB code: 6p9m was solved by G.C.Capodagli, M.B.Neiditch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.65 / 2.26
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	77.713, 77.713, 146.441, 90.00, 90.00, 120.00
R / Rfree (%)	19.7 / 23.2

The binding sites of Sodium atom in the Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J (pdb code 6p9m). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J, PDB code: 6p9m:

Sodium binding site 1 out of 1 in the Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Mycobacterium Tuberculosis Kasa in Complex with O6J within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:60.0 occ:1.00 OE1 A:GLU354 2.4 59.3 1.0 OD1 A:ASN399 2.4 54.2 1.0 O A:ASN309 2.4 52.1 1.0 OD1 A:ASN309 2.5 59.7 1.0 O A:ALA310 2.6 49.2 1.0 O A:ASN400 2.9 51.5 1.0 C A:ALA310 3.0 52.0 1.0 C A:ASN309 3.0 52.3 1.0 CD A:GLU354 3.4 55.8 1.0 CG A:ASN309 3.5 54.1 1.0 N A:HIS311 3.5 55.5 1.0 N A:ALA310 3.6 51.8 1.0 N A:ASN400 3.6 48.7 1.0 CG A:ASN399 3.6 55.3 1.0 CA A:ALA310 3.7 55.1 1.0 CB A:GLU354 3.8 41.6 1.0 CB A:ASN309 3.8 52.5 1.0 CA A:HIS311 3.9 53.3 1.0 C A:ASN400 3.9 48.2 1.0 CA A:ASN309 4.0 55.4 1.0 CG A:GLU354 4.1 45.0 1.0 OE2 A:GLU354 4.2 57.9 1.0 CA A:ASN400 4.3 49.5 1.0 C A:ASN399 4.5 53.1 1.0 ND2 A:ASN399 4.5 53.0 1.0 CA A:ASN399 4.5 55.4 1.0 O A:HOH650 4.6 59.2 1.0 ND2 A:ASN309 4.6 50.4 1.0 CB A:ASN399 4.6 51.8 1.0 CB A:ASN400 4.7 51.5 1.0 C A:HIS311 4.8 55.7 1.0 CD A:PRO339 4.8 54.1 1.0 OG A:SER401 4.9 53.3 0.6 CG A:PRO339 5.0 52.2 1.0

D.Inoyama, D.Awasthi, G.C.Capodagli, K.Tsotetsi, P.Sukheja, M.Zimmerman, S.G.Li, R.Jadhav, R.Russo, X.Wang, C.Grady, T.Richmann, R.Shrestha, L.Li, Y.M.Ahn, H.P.Ho Liang, M.Mina, S.Park, D.S.Perlin, N.Connell, V.Dartois, D.Alland, M.B.Neiditch, P.Kumar, J.S.Freundlich. A Preclinical Candidate Targeting Mycobacterium Tuberculosis Kasa. Cell Chem Biol 2020.
ISSN: ESSN 2451-9456
PubMed: 32197094
DOI: 10.1016/J.CHEMBIOL.2020.02.007