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Sodium in PDB 6hjx: X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72

Protein crystallography data

The structure of X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72, PDB code: 6hjx was solved by R.Spurny, C.Govaerts, G.L.Evans, E.Pardon, J.Steyaert, C.Ulens, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.59 / 2.50
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 96.251, 156.277, 102.496, 90.00, 102.88, 90.00
R / Rfree (%) 20.4 / 24.5

Sodium Binding Sites:

The binding sites of Sodium atom in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72 (pdb code 6hjx). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72, PDB code: 6hjx:

Sodium binding site 1 out of 1 in 6hjx

Go back to Sodium Binding Sites List in 6hjx
Sodium binding site 1 out of 1 in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) 7'C Pore Mutant (L238C) in Complex with Nanobody 72 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na403

b:74.7
occ:1.00
OG1 D:THR237 4.4 58.8 1.0
OG1 C:THR237 4.4 53.7 1.0

Reference:

C.M.Henault, C.Govaerts, R.Spurny, M.Brams, A.Estrada-Mondragon, J.Lynch, D.Bertrand, E.Pardon, G.L.Evans, K.Woods, B.W.Elberson, L.G.Cuello, G.Brannigan, H.Nury, J.Steyaert, J.E.Baenziger, C.Ulens. A Lipid Site Shapes the Agonist Response of A Pentameric Ligand-Gated Ion Channel. Nat.Chem.Biol. V. 15 1156 2019.
ISSN: ESSN 1552-4469
PubMed: 31591563
DOI: 10.1038/S41589-019-0369-4
Page generated: Tue Oct 8 09:20:13 2024

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