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Atomistry » Sodium » PDB 6go4-6h6m » 6h0u | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 6go4-6h6m » 6h0u » |
Sodium in PDB 6h0u: Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine InhibitorEnzymatic activity of Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor
All present enzymatic activity of Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor:
2.7.11.1; 2.7.11.26; Protein crystallography data
The structure of Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor, PDB code: 6h0u
was solved by
I.Marcovich,
N.Demitri,
R.De Zorzi,
P.Storici,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6h0u:
The structure of Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor
(pdb code 6h0u). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor, PDB code: 6h0u: Sodium binding site 1 out of 1 in 6h0uGo back to![]() ![]()
Sodium binding site 1 out
of 1 in the Glycogen Synthase Kinase-3 Beta (GSK3) Complex with A Covalent [1,2, 4]Triazolo[1,5-A][1,3,5]Triazine Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
S.Redenti,
I.Marcovich,
T.De Vita,
C.Perez,
R.De Zorzi,
N.Demitri,
D.I.Perez,
G.Bottegoni,
P.Bisignano,
M.Bissaro,
S.Moro,
A.Martinez,
P.Storici,
G.Spalluto,
A.Cavalli,
S.Federico.
A Triazolotriazine-Based Dual Gsk-3 Beta /Ck-1 Delta Ligand As A Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem V. 14 310 2019.
Page generated: Tue Oct 8 09:10:06 2024
ISSN: ESSN 1860-7187 PubMed: 30548443 DOI: 10.1002/CMDC.201800778 |
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