Sodium in PDB 6fwb: Crystal Structure of MAT2A at 1.79 Angstron Resolution

All present enzymatic activity of Crystal Structure of MAT2A at 1.79 Angstron Resolution:
2.5.1.6;

The structure of Crystal Structure of MAT2A at 1.79 Angstron Resolution, PDB code: 6fwb was solved by A.Zhou, Z.Wei, J.Bai, H.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.13 / 1.79
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	68.430, 103.027, 114.465, 90.00, 93.36, 90.00
R / Rfree (%)	17.2 / 18.3

The binding sites of Sodium atom in the Crystal Structure of MAT2A at 1.79 Angstron Resolution (pdb code 6fwb). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of MAT2A at 1.79 Angstron Resolution, PDB code: 6fwb:

Sodium binding site 1 out of 1 in the Crystal Structure of MAT2A at 1.79 Angstron Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of MAT2A at 1.79 Angstron Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Na410 b:33.9 occ:1.00 OD2 B:ASP43 2.9 22.5 1.0 C B:ILE370 3.4 24.3 1.0 N B:ARG373 3.4 22.4 1.0 O B:PRO369 3.4 27.2 1.0 N B:GLN372 3.4 20.1 1.0 CG B:ARG373 3.6 34.0 1.0 O B:ILE370 3.6 25.9 1.0 N B:TYR371 3.6 22.4 1.0 CA B:ILE370 3.7 25.7 1.0 CB B:GLN372 3.8 21.9 1.0 O5 B:PG4409 3.9 83.4 1.0 O B:HOH551 3.9 26.2 1.0 CA B:GLN372 3.9 21.0 1.0 CG B:ASP43 4.0 22.4 1.0 O B:HOH550 4.0 49.2 1.0 O4 B:PG4409 4.1 77.9 1.0 CB B:ARG373 4.1 28.6 1.0 C B:GLN372 4.1 21.3 1.0 C B:PRO369 4.1 26.0 1.0 C B:TYR371 4.2 20.9 1.0 N B:ILE370 4.2 24.6 1.0 CA B:ARG373 4.3 24.8 1.0 CD B:ARG373 4.4 38.5 1.0 O B:HOH608 4.4 37.5 1.0 OD1 B:ASP43 4.5 22.4 1.0 CA B:TYR371 4.5 21.2 1.0 C5 B:PG4409 4.6 68.2 1.0 O3 B:PG4409 4.7 63.3 1.0 C6 B:PG4409 4.9 72.2 1.0 C7 B:PG4409 4.9 79.2 1.0 CB B:ILE370 5.0 27.3 1.0 C8 B:PG4409 5.0 81.3 1.0

J.Bai, Y.Gao, L.Chen, Q.Yin, F.Lou, Z.Wang, Z.Xu, H.Zhou, Q.Li, W.Cai, Y.Sun, L.Niu, H.Wang, Z.Wei, S.Lu, A.Zhou, J.Zhang, H.Wang. Identification of A Natural Inhibitor of Methionine Adenosyltransferase 2A Regulating One-Carbon Metabolism in Keratinocytes. Ebiomedicine V. 39 575 2019.
ISSN: ESSN 2352-3964
PubMed: 30591370
DOI: 10.1016/J.EBIOM.2018.12.036