Sodium in PDB 6elr: Human JAK1 Kinase Domain in Complex with Compound 7

All present enzymatic activity of Human JAK1 Kinase Domain in Complex with Compound 7:
2.7.10.2;

The structure of Human JAK1 Kinase Domain in Complex with Compound 7, PDB code: 6elr was solved by J.A.Read, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.18 / 1.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.991, 174.093, 44.968, 90.00, 94.37, 90.00
R / Rfree (%)	18.1 / 20.5

The binding sites of Sodium atom in the Human JAK1 Kinase Domain in Complex with Compound 7 (pdb code 6elr). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human JAK1 Kinase Domain in Complex with Compound 7, PDB code: 6elr:

Sodium binding site 1 out of 1 in the Human JAK1 Kinase Domain in Complex with Compound 7


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human JAK1 Kinase Domain in Complex with Compound 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na1202 b:43.7 occ:1.00 O B:HOH1379 2.3 36.9 1.0 OD1 B:ASN976 2.8 21.7 1.0 O B:HOH1444 2.9 43.6 1.0 O B:HOH1304 3.1 38.6 1.0 CG B:ASN976 3.6 35.4 1.0 CB B:LYS978 3.7 21.7 1.0 ND2 B:ASN976 3.7 31.4 1.0 N B:GLN979 3.7 17.2 1.0 CG B:LYS978 3.9 31.3 1.0 CB B:GLN979 4.1 16.3 1.0 C B:LYS978 4.3 20.2 1.0 CA B:GLN979 4.3 15.8 1.0 CD B:LYS978 4.4 45.4 1.0 OE1 B:GLN979 4.4 22.6 1.0 CA B:LYS978 4.5 18.6 1.0 NZ B:LYS982 4.6 44.9 1.0 CE B:LYS982 4.9 41.6 1.0

N.P.Grimster, J.A.Read. Human JAK1 Kinase Domain in Complex with Compound 7 To Be Published.