Sodium in PDB 5tnz: HTRA2 S142D Mutant

All present enzymatic activity of HTRA2 S142D Mutant:
3.4.21.108;

The structure of HTRA2 S142D Mutant, PDB code: 5tnz was solved by S.Macedo-Ribeiro, M.Merski, P.J.B.Pereira, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.95 / 1.75
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	83.694, 83.694, 126.956, 90.00, 90.00, 120.00
R / Rfree (%)	14.4 / 17.2

The binding sites of Sodium atom in the HTRA2 S142D Mutant (pdb code 5tnz). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the HTRA2 S142D Mutant, PDB code: 5tnz:

Sodium binding site 1 out of 1 in the HTRA2 S142D Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of HTRA2 S142D Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Na502 b:28.2 occ:1.00 OE2 A:GLU376 2.2 28.8 1.0 O A:HOH712 2.6 34.1 1.0 OG A:SER372 3.0 33.1 0.5 CD A:GLU376 3.3 27.4 1.0 CG A:GLU376 3.7 28.4 1.0 CB A:SER372 4.2 32.7 0.5 CB A:SER372 4.3 32.7 0.5 OG A:SER372 4.3 34.0 0.5 OE1 A:GLU376 4.4 26.6 1.0 O A:HOH613 4.5 22.2 1.0 O A:HOH702 4.6 24.0 0.6 OE1 A:GLN296 4.7 27.7 1.0 CA A:SER372 4.9 32.1 0.5 CA A:SER372 4.9 32.1 0.5 O A:SER372 4.9 28.3 1.0

M.Merski, C.Moreira, R.M.Abreu, M.J.Ramos, P.A.Fernandes, L.M.Martins, P.J.B.Pereira, S.Macedo-Ribeiro. Molecular Motion Regulates the Activity of the Mitochondrial Serine Protease HTRA2. Cell Death Dis V. 8 E3119 2017.
ISSN: ISSN 2041-4889
PubMed: 29022916
DOI: 10.1038/CDDIS.2017.487