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Sodium in PDB 5ndd: Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution
Enzymatic activity of Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution
All present enzymatic activity of Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution:
3.2.1.17;
3.2.1.17;
Protein crystallography data
The structure of Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution, PDB code: 5ndd
was solved by
R.K.Y.Cheng,
C.Fiez-Vandal,
O.Schlenker,
K.Edman,
B.Aggeler,
D.G.Brown,
G.Brown,
R.M.Cooke,
C.E.Dumelin,
A.S.Dore,
S.Geschwindner,
C.Grebner,
N.-O.Hermansson,
A.Jazayeri,
P.Johansson,
L.Leong,
R.Prihandoko,
M.Rappas,
H.Soutter,
A.Snijder,
L.Sundstrom,
B.Tehan,
P.Thornton,
D.Troast,
G.Wiggin,
A.Zhukov,
F.H.Marshall,
N.Dekker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 34.34 / 2.80 |
| Space group | P 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 37.109, 62.264, 87.341, 104.88, 90.88, 96.89 |
| R / Rfree (%) | 22.2 / 26.4 |
Other elements in 5ndd:
The structure of Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution
(pdb code 5ndd). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution, PDB code: 5ndd:
In total only one binding site of Sodium was determined in the Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution, PDB code: 5ndd:
Sodium binding site 1 out of 1 in 5ndd
Go back to
Sodium Binding Sites List in 5ndd
Sodium binding site 1 out
of 1 in the Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Crystal Structure of A Thermostabilised Human Protease-Activated Receptor-2 (PAR2) in Complex with AZ8838 at 2.8 Angstrom Resolution within 5.0Å range:
|
Reference:
R.K.Y.Cheng,
C.Fiez-Vandal,
O.Schlenker,
K.Edman,
B.Aggeler,
D.G.Brown,
G.A.Brown,
R.M.Cooke,
C.E.Dumelin,
A.S.Dore,
S.Geschwindner,
C.Grebner,
N.O.Hermansson,
A.Jazayeri,
P.Johansson,
L.Leong,
R.Prihandoko,
M.Rappas,
H.Soutter,
A.Snijder,
L.Sundstrom,
B.Tehan,
P.Thornton,
D.Troast,
G.Wiggin,
A.Zhukov,
F.H.Marshall,
N.Dekker.
Structural Insight Into Allosteric Modulation of Protease-Activated Receptor 2. Nature V. 545 112 2017.
ISSN: ESSN 1476-4687
PubMed: 28445455
DOI: 10.1038/NATURE22309
Page generated: Mon Oct 7 22:55:52 2024
ISSN: ESSN 1476-4687
PubMed: 28445455
DOI: 10.1038/NATURE22309
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