Sodium in PDB 5mzv: Il-23:Il-23R:NB22E11 Complex

The structure of Il-23:Il-23R:NB22E11 Complex, PDB code: 5mzv was solved by Y.Bloch, S.N.Savvides, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	76.85 / 2.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	67.219, 112.190, 109.870, 90.00, 106.24, 90.00
R / Rfree (%)	21.2 / 25

The structure of Il-23:Il-23R:NB22E11 Complex also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Sodium atom in the Il-23:Il-23R:NB22E11 Complex (pdb code 5mzv). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Il-23:Il-23R:NB22E11 Complex, PDB code: 5mzv:

Sodium binding site 1 out of 1 in the Il-23:Il-23R:NB22E11 Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Il-23:Il-23R:NB22E11 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Na402 b:57.5 occ:1.00 OD1 A:ASP84 2.7 49.0 1.0 O A:HOH523 3.3 57.7 1.0 O A:HOH516 3.5 57.7 1.0 CG A:ASP84 3.8 49.6 1.0 OD2 A:ASP84 4.1 49.9 1.0 HZ1 A:LYS80 4.6 54.6 1.0 HZ3 A:LYS80 4.6 54.6 1.0 OE2 A:GLU81 4.9 47.0 1.0 HA A:ASP84 4.9 52.1 1.0 HE2 A:LYS80 4.9 54.2 1.0

Y.Bloch, L.Bouchareychas, R.Merceron, K.Skladanowska, L.Van Den Bossche, S.Detry, S.Govindarajan, D.Elewaut, F.Haerynck, M.Dullaers, I.E.Adamopoulos, S.N.Savvides. Structural Activation of Pro-Inflammatory Human Cytokine Il-23 By Cognate Il-23 Receptor Enables Recruitment of the Shared Receptor Il-12R Beta 1. Immunity V. 48 45 2018.
ISSN: ISSN 1097-4180
PubMed: 29287995
DOI: 10.1016/J.IMMUNI.2017.12.008