Sodium in PDB 5kxq: Mouse POFUT1 in Complex with Gdp

All present enzymatic activity of Mouse POFUT1 in Complex with Gdp:
2.4.1.221;

The structure of Mouse POFUT1 in Complex with Gdp, PDB code: 5kxq was solved by Z.Li, J.M.Rini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.50 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.140, 251.820, 56.080, 90.00, 95.81, 90.00
R / Rfree (%)	16.2 / 19.1

The binding sites of Sodium atom in the Mouse POFUT1 in Complex with Gdp (pdb code 5kxq). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Mouse POFUT1 in Complex with Gdp, PDB code: 5kxq:

Sodium binding site 1 out of 1 in the Mouse POFUT1 in Complex with Gdp


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Mouse POFUT1 in Complex with Gdp within 5.0Å range: probe atom residue distance (Å) B Occ C:Na404 b:46.5 occ:1.00 O C:HOH581 2.2 40.6 1.0 O B:HOH641 2.3 53.6 1.0 O B:HOH576 2.5 30.5 1.0 NE2 C:GLN351 2.6 29.5 1.0 O B:HOH562 2.6 25.7 1.0 O B:ALA233 2.8 20.7 1.0 CD C:GLN351 3.2 30.1 1.0 OE1 C:GLN351 3.4 35.1 1.0 C B:ALA233 3.7 21.9 1.0 CA B:ALA233 4.0 22.9 1.0 O C:HOH592 4.0 34.0 1.0 OE2 C:GLU228 4.1 22.7 1.0 O B:HOH582 4.2 23.5 1.0 OH C:TYR347 4.2 21.2 1.0 O C:HOH588 4.3 43.6 1.0 O C:HOH682 4.5 40.1 1.0 O B:SER232 4.5 22.2 1.0 CG C:GLN351 4.5 22.2 1.0 O C:HOH699 4.7 48.6 1.0 NH1 C:ARG376 4.8 49.9 1.0 CB B:ALA233 4.8 23.4 1.0 NH1 B:ARG333 4.9 42.9 1.0 N B:HIS234 4.9 20.5 1.0

Z.Li, K.Han, J.E.Pak, M.Satkunarajah, D.Zhou, J.M.Rini. Recognition of Egf-Like Domains By the Notch-Modifying O-Fucosyltransferase POFUT1. Nat. Chem. Biol. V. 13 757 2017.
ISSN: ESSN 1552-4469
PubMed: 28530709
DOI: 10.1038/NCHEMBIO.2381