Sodium in PDB 5jrp: Crystal Structure of Monoclonal Antibody MR78 Fab

The structure of Crystal Structure of Monoclonal Antibody MR78 Fab, PDB code: 5jrp was solved by J.Dong, J.Crowe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	117.570, 117.570, 91.800, 90.00, 90.00, 120.00
R / Rfree (%)	17.1 / 19.4

The binding sites of Sodium atom in the Crystal Structure of Monoclonal Antibody MR78 Fab (pdb code 5jrp). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Monoclonal Antibody MR78 Fab, PDB code: 5jrp:

Sodium binding site 1 out of 1 in the Crystal Structure of Monoclonal Antibody MR78 Fab


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Monoclonal Antibody MR78 Fab within 5.0Å range: probe atom residue distance (Å) B Occ L:Na301 b:26.1 occ:1.00 O L:HOH567 2.9 56.7 1.0 OG L:SER7 3.1 36.5 1.0 OG1 L:THR5 3.2 31.6 1.0 OG1 L:THR22 3.2 36.0 1.0 N L:SER7 3.5 23.9 1.0 O L:THR22 3.7 21.8 1.0 CB L:SER7 3.8 29.2 1.0 CA L:GLN6 3.8 21.2 1.0 O L:THR5 3.8 23.4 1.0 C L:GLN6 3.8 24.6 1.0 C L:THR5 3.8 25.4 1.0 C L:THR22 3.9 21.7 1.0 N L:GLN6 3.9 23.4 1.0 N L:GLN24 4.0 20.8 1.0 CB L:THR5 4.0 32.1 1.0 N L:CYS23 4.1 21.3 1.0 CB L:THR22 4.1 29.4 1.0 O L:HOH540 4.1 57.4 1.0 CA L:CYS23 4.1 23.2 1.0 C L:CYS23 4.1 22.9 1.0 CG L:GLN24 4.2 50.5 1.0 CA L:SER7 4.3 27.5 1.0 CB L:GLN24 4.4 36.9 1.0 O L:HOH551 4.6 51.8 1.0 O L:GLN6 4.6 26.5 1.0 CA L:THR5 4.6 27.5 1.0 OE1 L:GLN24 4.6 66.9 1.0 CA L:THR22 4.6 21.7 1.0 O L:CYS23 4.8 22.3 1.0 CD L:GLN24 4.8 60.7 1.0 CA L:GLN24 4.8 26.4 1.0

A.K.Sangha, J.Dong, L.Williamson, T.Hashiguchi, E.O.Saphire, J.E.Crowe, J.Meiler. Role of Non-Local Interactions Between Cdr Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure V. 25 1820 2017.
ISSN: ISSN 1878-4186
PubMed: 29153506
DOI: 10.1016/J.STR.2017.10.005