Sodium in PDB 4uug: The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound

All present enzymatic activity of The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound:
2.6.1.42;

The structure of The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound, PDB code: 4uug was solved by M.Thomsen, W.Hinrichs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.25 / 1.60
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	144.449, 144.449, 96.112, 90.00, 90.00, 120.00
R / Rfree (%)	13.376 / 14.811

The binding sites of Sodium atom in the The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound (pdb code 4uug). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound, PDB code: 4uug:

Sodium binding site 1 out of 1 in the The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The (R)-Selective Amine Transaminase From Aspergillus Fumigatus with Inhibitor Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:Na406 b:11.6 occ:0.70 O B:LEU133 2.2 15.3 0.7 O B:ASN136 2.3 15.0 0.7 O B:HOH2182 2.4 19.6 1.0 OD1 B:ASN137 2.4 15.4 1.0 O B:HOH2181 2.5 27.2 1.0 O B:ASN136 2.6 15.7 0.3 O B:HOH2191 2.7 17.3 1.0 OD1 B:ASN135 3.1 18.0 0.3 C B:LEU133 3.3 16.8 0.7 C B:ASN136 3.4 15.2 0.7 C B:ASN136 3.5 15.6 0.3 CG B:ASN137 3.5 14.5 1.0 CA B:ASN137 3.6 13.3 1.0 O2 B:FMT405 3.8 19.9 0.5 O B:HOH2183 3.8 29.2 1.0 N B:ASN137 3.9 13.3 1.0 CB B:ASN137 4.1 13.7 1.0 O B:HOH2192 4.1 25.3 1.0 CA B:TYR134 4.1 17.7 0.7 O2 B:FMT405 4.2 16.6 0.5 N B:TYR134 4.2 17.3 0.7 CG B:ASN135 4.3 18.4 0.3 CA B:LEU133 4.3 17.5 0.7 CB B:LEU133 4.3 17.3 0.7 N B:ASN136 4.5 15.5 0.7 O B:ASN135 4.5 17.7 0.3 CA B:ASN136 4.5 15.4 0.7 N B:ASN136 4.5 16.7 0.3 C B:ASN135 4.6 17.8 0.3 CA B:ASN136 4.6 15.9 0.3 C B:TYR134 4.6 17.5 0.7 ND2 B:ASN137 4.6 14.9 1.0 C B:ASN137 4.7 12.9 1.0 N B:ILE138 4.8 12.7 1.0 ND2 B:ASN135 5.0 18.9 0.3

L.Skalden, M.Thomsen, M.Hohne, U.T.Bornscheuer, W.Hinrichs. Structural and Biochemical Characterization of the Dual Substrate Recognition of the (R)-Selective Amine Transaminase From Aspergillus Fumigatus Febs J. 2014.
ISSN: ESSN 1742-4658
PubMed: 25400251
DOI: 10.1111/FEBS.13149