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Atomistry » Sodium » PDB 4u9u-4us7 » 4und | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 4u9u-4us7 » 4und » |
Sodium in PDB 4und: Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor TalazoparibEnzymatic activity of Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib
All present enzymatic activity of Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib:
2.4.2.30; Protein crystallography data
The structure of Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib, PDB code: 4und
was solved by
T.Karlberg,
A.G.Thorsell,
T.Ekblad,
M.Klepsch,
A.F.Pinto,
L.Tresaugues,
M.Moche,
H.Schuler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4und:
The structure of Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib
(pdb code 4und). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib, PDB code: 4und: Sodium binding site 1 out of 1 in 4undGo back to![]() ![]()
Sodium binding site 1 out
of 1 in the Human ARTD1 (PARP1) - Catalytic Domain in Complex with Inhibitor Talazoparib
![]() Mono view ![]() Stereo pair view
Reference:
A.G.Thorsell,
T.Ekblad,
T.Karlberg,
M.Low,
A.F.Pinto,
L.Tresaugues,
M.Moche,
M.S.Cohen,
H.Schuler.
Structural Basis For Potency and Promiscuity in Poly(Adp-Ribose) Polymerase (Parp) and Tankyrase Inhibitors. J. Med. Chem. V. 60 1262 2017.
Page generated: Mon Oct 7 18:40:47 2024
ISSN: ISSN 1520-4804 PubMed: 28001384 DOI: 10.1021/ACS.JMEDCHEM.6B00990 |
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