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Sodium in PDB 4poe: Urate Oxidase Co-Crystallized with Uric Acid and Azide

Enzymatic activity of Urate Oxidase Co-Crystallized with Uric Acid and Azide

All present enzymatic activity of Urate Oxidase Co-Crystallized with Uric Acid and Azide:
1.7.3.3;

Protein crystallography data

The structure of Urate Oxidase Co-Crystallized with Uric Acid and Azide, PDB code: 4poe was solved by N.Colloc'h, T.Prange, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.00 / 1.07
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 79.524, 95.240, 104.577, 90.00, 90.00, 90.00
R / Rfree (%) 18.5 / n/a

Sodium Binding Sites:

The binding sites of Sodium atom in the Urate Oxidase Co-Crystallized with Uric Acid and Azide (pdb code 4poe). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase Co-Crystallized with Uric Acid and Azide, PDB code: 4poe:

Sodium binding site 1 out of 1 in 4poe

Go back to Sodium Binding Sites List in 4poe
Sodium binding site 1 out of 1 in the Urate Oxidase Co-Crystallized with Uric Acid and Azide


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase Co-Crystallized with Uric Acid and Azide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na404

b:14.5
occ:1.00
O A:ILE94 2.3 13.7 1.0
O A:ILE88 2.3 16.7 1.0
O A:HOH1145 2.4 23.8 1.0
O A:TYR91 2.4 14.6 1.0
OE1 A:GLU136 2.5 23.4 1.0
O A:ASN92 3.0 24.3 1.0
C A:ILE88 3.4 14.0 1.0
C A:ILE94 3.4 13.3 1.0
C A:ASN92 3.4 18.2 1.0
C A:TYR91 3.5 14.5 1.0
CD A:GLU136 3.5 30.9 1.0
CA A:ASN92 3.7 16.8 1.0
CA A:ILE88 3.7 13.0 1.0
N A:ILE94 3.9 13.1 1.0
ND1 A:HIS95 4.0 20.5 1.0
N A:ASN92 4.0 17.0 1.0
OE2 A:GLU136 4.1 67.8 1.0
CB A:ILE88 4.1 13.0 1.0
CA A:ILE94 4.2 12.5 1.0
N A:HIS93 4.3 14.7 1.0
O A:HOH1172 4.3 39.4 1.0
N A:HIS95 4.4 13.2 1.0
O A:HOH1218 4.5 28.4 1.0
N A:GLU89 4.5 14.2 1.0
CE1 A:HIS95 4.5 20.4 1.0
CA A:HIS95 4.6 13.4 1.0
O A:PHE87 4.7 13.9 1.0
CB A:ILE94 4.7 11.9 1.0
CG A:GLU136 4.7 24.7 1.0
C A:HIS93 4.7 13.6 1.0
CA A:TYR91 4.7 13.7 1.0
N A:TYR91 4.8 13.2 1.0
CA A:GLU89 4.9 14.9 1.0
CA A:HIS93 5.0 14.2 1.0

Reference:

L.Gabison, N.Colloc'h, T.Prange. Azide Inhibition of Urate Oxidase. Acta Crystallogr.,Sect.F V. 70 896 2014.
ISSN: ISSN 1744-3091
PubMed: 25005084
DOI: 10.1107/S2053230X14011753
Page generated: Mon Oct 7 17:46:28 2024

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