Atomistry » Sodium » PDB 4pd8-4pp4 » 4pod
Atomistry »
  Sodium »
    PDB 4pd8-4pp4 »
      4pod »

Sodium in PDB 4pod: Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme.

Enzymatic activity of Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme.

All present enzymatic activity of Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme.:
5.3.1.1;

Protein crystallography data

The structure of Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme., PDB code: 4pod was solved by C.G.Amrich, A.A.Aslam, A.Heroux, A.P.Vandemark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.49 / 1.99
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 63.659, 70.729, 91.749, 90.00, 90.00, 90.00
R / Rfree (%) 17 / 21.3

Other elements in 4pod:

The structure of Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme. also contains other interesting chemical elements:

Potassium (K) 2 atoms
Bromine (Br) 1 atom

Sodium Binding Sites:

The binding sites of Sodium atom in the Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme. (pdb code 4pod). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme., PDB code: 4pod:

Sodium binding site 1 out of 1 in 4pod

Go back to Sodium Binding Sites List in 4pod
Sodium binding site 1 out of 1 in the Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme.


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of Triosephosphate Isomerase I170V Mutant Human Enzyme. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na302

b:76.5
occ:1.00
 HD2 A:PRO57 2.9 49.7 1.0
OD2 A:ASP56 3.1 64.3 1.0
HG2 A:PRO57 3.5 50.8 1.0
OD1 A:ASP56 3.6 61.1 1.0
CG A:ASP56 3.7 60.9 1.0
CD A:PRO57 3.8 41.4 1.0
CG A:PRO57 4.1 42.4 1.0
HD3 A:PRO57 4.2 49.7 1.0
HB2 A:PRO57 4.4 48.2 1.0
CB A:PRO57 4.8 40.2 1.0
N A:PRO57 4.8 38.8 1.0
HG3 A:PRO57 4.9 50.8 1.0
H A:LYS58 5.0 39.5 1.0

Reference:

B.P.Roland, C.G.Amrich, C.J.Kammerer, K.A.Stuchul, S.B.Larsen, S.Rode, A.A.Aslam, A.Heroux, R.Wetzel, A.P.Vandemark, M.J.Palladino. Triosephosphate Isomerase I170V Alters Catalytic Site, Enhances Stability and Induces Pathology in A Drosophila Model of Tpi Deficiency. Biochim.Biophys.Acta V.1852 61 2015.
ISSN: ISSN 0006-3002
PubMed: 25463631
DOI: 10.1016/J.BBADIS.2014.10.010
Page generated: Mon Oct 7 17:46:18 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy