Sodium in PDB 4l8g: Crystal Structure of K-Ras G12C, Gdp-Bound

The structure of Crystal Structure of K-Ras G12C, Gdp-Bound, PDB code: 4l8g was solved by J.M.Ostrem, U.Peters, M.L.Sos, J.A.Wells, K.M.Shokat, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.73 / 1.52
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	82.146, 82.146, 39.513, 90.00, 90.00, 120.00
R / Rfree (%)	14.8 / 18

The structure of Crystal Structure of K-Ras G12C, Gdp-Bound also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Sodium atom in the Crystal Structure of K-Ras G12C, Gdp-Bound (pdb code 4l8g). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of K-Ras G12C, Gdp-Bound, PDB code: 4l8g:

Sodium binding site 1 out of 1 in the Crystal Structure of K-Ras G12C, Gdp-Bound


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of K-Ras G12C, Gdp-Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Na203 b:17.3 occ:0.33 O A:HOH369 2.4 48.0 0.3 O A:HOH330 2.5 29.1 1.0 O A:HOH325 2.5 29.2 1.0 O A:HOH335 4.4 27.5 1.0 O A:THR124 4.4 21.9 1.0 OE1 A:GLN129 4.9 30.1 1.0

J.M.Ostrem, U.Peters, M.L.Sos, J.A.Wells, K.M.Shokat. K-Ras(G12C) Inhibitors Allosterically Control Gtp Affinity and Effector Interactions. Nature V. 503 548 2013.
ISSN: ISSN 0028-0836
PubMed: 24256730
DOI: 10.1038/NATURE12796