Sodium in PDB 4kfm: Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits

The structure of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits, PDB code: 4kfm was solved by M.R.Whorton, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.89 / 3.45
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.308, 127.308, 309.392, 90.00, 90.00, 90.00
R / Rfree (%)	22.8 / 26.5

The structure of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits also contains other interesting chemical elements:

Potassium

(K)

5 atoms

The binding sites of Sodium atom in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits (pdb code 4kfm). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits, PDB code: 4kfm:

Sodium binding site 1 out of 1 in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with the Beta-Gamma G Protein Subunits within 5.0Å range: probe atom residue distance (Å) B Occ A:Na407 b:97.1 occ:1.00 OD2 A:ASP228 2.5 0.3 1.0 O A:ARG230 2.9 99.8 1.0 O A:SER232 3.3 0.6 1.0 CG A:ASP228 3.5 0.6 1.0 O A:LEU275 3.6 0.4 1.0 O A:VAL276 3.8 0.8 1.0 CA A:VAL276 3.9 0.6 1.0 CB A:ASP228 4.0 0.8 1.0 C A:ARG230 4.1 0.9 1.0 ND1 A:HIS233 4.2 0.7 1.0 O A:ASP228 4.2 0.7 1.0 O A:ASN231 4.2 0.4 1.0 C A:VAL276 4.3 0.3 1.0 C A:SER232 4.4 0.1 1.0 C A:ASN231 4.4 0.6 1.0 C A:LEU275 4.5 100.0 1.0 CG1 A:VAL276 4.5 0.9 1.0 OD1 A:ASP228 4.5 0.8 1.0 CA A:ASN231 4.7 0.1 1.0 CB A:VAL276 4.7 0.5 1.0 CE1 A:HIS233 4.7 0.8 1.0 N A:VAL276 4.7 0.4 1.0 N A:ASN231 4.9 0.5 1.0 C A:ASP228 4.9 99.8 1.0 CA A:HIS233 4.9 1.0 1.0 CG2 A:VAL276 4.9 0.2 1.0 N A:SER232 4.9 0.2 1.0

M.R.Whorton, R.Mackinnon. X-Ray Structure of the Mammalian GIRK2-Beta Gamma G-Protein Complex. Nature V. 498 190 2013.
ISSN: ISSN 0028-0836
PubMed: 23739333
DOI: 10.1038/NATURE12241