Sodium in PDB 4fkp: Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor

All present enzymatic activity of Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor:
2.7.11.22;

The structure of Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor, PDB code: 4fkp was solved by Y.N.Kang, J.A.Stuckey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.93 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.290, 71.260, 72.000, 90.00, 90.00, 90.00
R / Rfree (%)	18.4 / 19.8

The binding sites of Sodium atom in the Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor (pdb code 4fkp). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor, PDB code: 4fkp:

Sodium binding site 1 out of 1 in the Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:34.5 occ:1.00 O A:HOH445 2.7 26.2 1.0 OD1 A:ASN59 2.7 25.2 1.0 O A:HOH437 3.0 16.5 1.0 N A:LEU66 3.1 17.5 1.0 CA A:LYS65 3.2 16.2 0.5 CA A:LYS65 3.2 16.5 0.5 O A:LEU58 3.3 25.0 1.0 C A:LYS65 3.7 19.0 1.0 CG A:LYS65 3.8 21.3 0.5 O A:VAL64 3.8 17.7 1.0 CG A:ASN59 3.9 26.5 1.0 CG A:LYS65 3.9 30.8 0.5 O A:HOH520 3.9 30.9 1.0 O A:HOH504 3.9 31.9 1.0 CB A:LYS65 3.9 19.2 0.5 C A:LEU58 4.0 24.3 1.0 CB A:LYS65 4.0 19.9 0.5 O A:LEU55 4.0 25.1 1.0 CA A:ASN59 4.2 17.9 1.0 N A:LYS65 4.2 16.8 1.0 CA A:LEU66 4.2 18.4 0.3 CB A:LEU66 4.2 19.5 0.3 CA A:LEU66 4.2 16.9 0.7 C A:VAL64 4.3 16.8 1.0 CB A:LEU66 4.3 17.1 0.7 N A:ASN59 4.4 19.6 1.0 O A:LEU66 4.4 23.0 1.0 CG2 A:ILE63 4.5 17.0 0.5 CB A:ASN59 4.5 18.0 1.0 O A:LYS56 4.6 30.6 1.0 CG2 A:ILE63 4.6 15.3 0.5 C A:LEU66 4.7 22.7 1.0 O A:ILE63 4.9 16.2 1.0 O A:LYS65 4.9 17.7 1.0 ND2 A:ASN59 4.9 29.9 1.0 C A:LYS56 5.0 29.5 1.0

Y.N.Kang, J.A.Stuckey. Crystal Structure of the CDK2 in Complex with Oxindole Inhibitor To Be Published.