Sodium in PDB 4eiy: Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution

The structure of Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution, PDB code: 4eiy was solved by W.Liu, E.Chun, A.A.Thompson, P.Chubukov, F.Xu, V.Katritch, G.W.Han, L.H.Heitman, A.P.Ijzerman, V.Cherezov, R.C.Stevens, Gpcr Network (Gpcr), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.73 / 1.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	39.442, 179.516, 140.307, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 21.3

The binding sites of Sodium atom in the Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution (pdb code 4eiy). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution, PDB code: 4eiy:

Sodium binding site 1 out of 1 in the Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Chimeric Protein of A2AAR-Bril in Complex with ZM241385 at 1.8A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na2402 b:27.8 occ:1.00 O A:HOH2552 2.2 28.4 1.0 O A:HOH2529 2.4 21.7 1.0 OD1 A:ASP52 2.5 19.8 1.0 OG A:SER91 2.5 15.7 1.0 O A:HOH2579 2.6 26.8 1.0 CG A:ASP52 3.4 21.7 1.0 CB A:SER91 3.4 16.2 1.0 OD2 A:ASP52 3.6 22.0 1.0 OD1 A:ASN280 3.9 17.9 1.0 O A:HOH2608 4.0 32.6 1.0 CD1 A:LEU48 4.2 16.3 1.0 OG A:SER281 4.2 18.4 1.0 O A:HOH2528 4.3 19.3 1.0 O A:HOH2553 4.4 28.6 1.0 CE1 A:PHE242 4.5 17.3 1.0 CB A:ASP52 4.7 17.9 1.0 CD1 A:PHE242 4.7 15.2 1.0 CA A:SER91 4.8 13.9 1.0 CB A:ALA51 4.8 14.2 1.0 O A:LEU87 4.8 17.8 1.0 N A:ASP52 4.8 14.8 1.0 CA A:ASP52 4.9 16.3 1.0 O A:LEU48 4.9 14.3 1.0

W.Liu, E.Chun, A.A.Thompson, P.Chubukov, F.Xu, V.Katritch, G.W.Han, C.B.Roth, L.H.Heitman, A.P.Ijzerman, V.Cherezov, R.C.Stevens. Structural Basis For Allosteric Regulation of Gpcrs By Sodium Ions. Science V. 337 232 2012.
ISSN: ISSN 0036-8075
PubMed: 22798613
DOI: 10.1126/SCIENCE.1219218