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Atomistry » Sodium » PDB 3r9b-3rn1 » 3rm2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 3r9b-3rn1 » 3rm2 » |
Sodium in PDB 3rm2: Human Thrombin in Complex with MI003Enzymatic activity of Human Thrombin in Complex with MI003
All present enzymatic activity of Human Thrombin in Complex with MI003:
3.4.21.5; Protein crystallography data
The structure of Human Thrombin in Complex with MI003, PDB code: 3rm2
was solved by
A.Biela,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Thrombin in Complex with MI003
(pdb code 3rm2). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Thrombin in Complex with MI003, PDB code: 3rm2: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 3rm2Go back to![]() ![]()
Sodium binding site 1 out
of 2 in the Human Thrombin in Complex with MI003
![]() Mono view ![]() Stereo pair view
Sodium binding site 2 out of 2 in 3rm2Go back to![]() ![]()
Sodium binding site 2 out
of 2 in the Human Thrombin in Complex with MI003
![]() Mono view ![]() Stereo pair view
Reference:
A.Biela,
F.Sielaff,
F.Terwesten,
A.Heine,
T.Steinmetzer,
G.Klebe.
Ligand Binding Stepwise Disrupts Water Network in Thrombin: Enthalpic and Entropic Changes Reveal Classical Hydrophobic Effect J.Med.Chem. V. 55 6094 2012.
Page generated: Mon Oct 7 12:49:55 2024
ISSN: ISSN 0022-2623 PubMed: 22612268 DOI: 10.1021/JM300337Q |
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