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Atomistry » Sodium » PDB 3ogc-3p1l » 3p0q » |
Sodium in PDB 3p0q: Human Tankyrase 2 - Catalytic Parp Domain in Complex with An InhibitorEnzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
All present enzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor:
2.4.2.30; Protein crystallography data
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0q
was solved by
T.Karlberg,
M.I.Siponen,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Kotenyova,
E.Kouznetsova,
M.Moche,
P.Nordlund,
T.Nyman,
C.Persson,
P.Schutz,
A.Sehic,
A.G.Thorsell,
L.Tresaugues,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Welin,
H.Schuler,
Structural Genomicsconsortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3p0q:
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
(pdb code 3p0q). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0q: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 3p0qGo back to![]() ![]()
Sodium binding site 1 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
![]() Mono view ![]() Stereo pair view
Sodium binding site 2 out of 2 in 3p0qGo back to![]() ![]()
Sodium binding site 2 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
E.Wahlberg,
T.Karlberg,
E.Kouznetsova,
N.Markova,
A.Macchiarulo,
A.G.Thorsell,
E.Pol,
A.Frostell,
T.Ekblad,
B.Kull,
G.M.Robertson,
R.Pellicciari,
H.Schuler,
J.Weigelt.
Family-Wide Chemical Profiling and Structural Analysis of Parp and Tankyrase Inhibitors Nat.Biotechnol. V. 30 283 2012.
Page generated: Mon Oct 7 12:07:50 2024
ISSN: ISSN 1087-0156 PubMed: 22343925 DOI: 10.1038/NBT.2121 |
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