Sodium in PDB 2ycy: Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol

The structure of Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol, PDB code: 2ycy was solved by R.Moukhametzianov, T.Warne, P.C.Edwards, M.J.Serrano-Vega, A.G.W.Leslie, C.G.Tate, G.F.X.Schertler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.51 / 3.15
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	184.760, 56.161, 89.778, 90.00, 111.27, 90.00
R / Rfree (%)	25.4 / 29.2

The binding sites of Sodium atom in the Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol (pdb code 2ycy). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol, PDB code: 2ycy:

Sodium binding site 1 out of 1 in the Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Turkey BETA1 Adrenergic Receptor with Stabilising Mutations and Bound Antagonist Cyanopindolol within 5.0Å range: probe atom residue distance (Å) B Occ B:Na1363 b:65.5 occ:1.00 O B:CYS198 2.3 54.7 1.0 O B:ASP195 2.5 60.3 1.0 O B:CYS192 2.5 58.4 1.0 C B:CYS198 3.4 53.8 1.0 C B:CYS192 3.7 58.2 1.0 C B:ASP195 3.7 60.5 1.0 CB B:CYS198 3.9 54.8 1.0 CA B:CYS198 4.0 54.8 1.0 O B:TYR193 4.0 60.8 1.0 CA B:TYR193 4.0 58.7 1.0 N B:CYS198 4.1 53.8 1.0 C B:TYR193 4.2 61.4 1.0 N B:TYR193 4.3 58.2 1.0 SG B:CYS192 4.4 72.3 1.0 N B:CYS199 4.4 51.9 1.0 OG B:SER111 4.4 57.0 1.0 N B:ASP195 4.5 65.8 1.0 CA B:ASP195 4.6 63.7 1.0 N B:PRO196 4.6 56.6 1.0 CA B:PRO196 4.6 54.3 1.0 CA B:CYS199 4.8 51.3 1.0 C B:PRO196 4.8 53.3 1.0 SG B:CYS114 4.8 42.1 1.0 CA B:CYS192 4.8 58.9 1.0 SG B:CYS198 4.8 69.2 1.0 CB B:ASP195 4.9 64.6 1.0 O B:HOH2001 4.9 17.0 1.0

R.Moukhametzianov, T.Warne, P.C.Edwards, M.J.Serrano-Vega, A.G.W.Leslie, C.G.Tate, G.F.X.Schertler. Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of A {Beta}1- Adrenergic Receptor. Proc.Natl.Acad.Sci.Usa V. 108 8228 2011.
ISSN: ISSN 0027-8424
PubMed: 21540331
DOI: 10.1073/PNAS.1100185108