Atomistry » Sodium » PDB 2ekb-2fm1 » 2evc
Atomistry »
  Sodium »
    PDB 2ekb-2fm1 »
      2evc »

Sodium in PDB 2evc: Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid

Enzymatic activity of Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid

All present enzymatic activity of Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid:
3.4.11.18;

Protein crystallography data

The structure of Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid, PDB code: 2evc was solved by W.-J.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 1.60
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 37.800, 60.200, 50.400, 90.00, 104.50, 90.00
R / Rfree (%) 21 / 22.9

Other elements in 2evc:

The structure of Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid also contains other interesting chemical elements:

Fluorine (F) 3 atoms
Manganese (Mn) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid (pdb code 2evc). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid, PDB code: 2evc:

Sodium binding site 1 out of 1 in 2evc

Go back to Sodium Binding Sites List in 2evc
Sodium binding site 1 out of 1 in the Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of E. Coli. Methionine Amino Peptidase in Complex with 5-(2-(Trifluoromethyl)Phenyl)Furan-2- Carboxylic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na903

b:12.7
occ:1.00
 O A:ASN74 2.1 12.4 1.0
O A:SER231 2.2 10.8 1.0
O A:HOH1009 2.3 12.6 1.0
O A:VAL76 2.3 12.4 1.0
C A:ASN74 3.1 13.2 1.0
C A:SER231 3.3 10.4 1.0
C A:VAL76 3.5 12.0 1.0
N A:ASN74 3.6 11.8 1.0
CA A:ASN74 3.7 12.2 1.0
O A:HOH1037 3.8 12.6 1.0
N A:SER231 3.8 11.9 1.0
C A:ILE73 3.8 11.4 1.0
N A:VAL76 3.8 11.0 1.0
CA A:SER231 3.8 11.4 1.0
CB A:SER231 3.9 11.5 1.0
O A:ILE73 4.0 12.5 1.0
N A:GLU75 4.1 14.7 1.0
CA A:VAL76 4.2 11.8 1.0
C A:GLU75 4.2 13.6 1.0
O A:SER72 4.3 12.4 1.0
N A:ALA232 4.4 9.3 1.0
N A:VAL77 4.4 10.8 1.0
C A:SER72 4.5 13.4 1.0
O A:HOH1012 4.5 9.8 1.0
CA A:GLU75 4.5 14.5 1.0
CA A:ILE73 4.6 12.4 1.0
CA A:VAL77 4.6 11.6 1.0
N A:ILE73 4.6 11.6 1.0
OG A:SER231 4.7 11.2 1.0
CD1 A:ILE93 4.7 16.0 1.0
CB A:SER72 4.7 10.4 1.0
CA A:ALA232 4.7 10.2 1.0
CG1 A:ILE93 4.8 12.0 1.0
CB A:VAL76 4.8 10.9 1.0
CE A:MET112 4.8 9.5 1.0
O A:ILE93 4.9 11.3 1.0
O A:GLU75 4.9 13.6 1.0

Reference:

S.X.Xie, W.J.Huang, Z.Q.Ma, M.Huang, R.P.Hanzlik, Q.Z.Ye. Structural Analysis of Metalloform-Selective Inhibition of Methionine Aminopeptidase. Acta Crystallogr.,Sect.D V. 62 425 2006.
ISSN: ISSN 0907-4449
PubMed: 16552144
DOI: 10.1107/S0907444906003878
Page generated: Mon Oct 7 02:24:37 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy