Sodium in PDB 9iti: NAV1.7 with Mutations That Eliminate BETA1 Binding

The binding sites of Sodium atom in the NAV1.7 with Mutations That Eliminate BETA1 Binding (pdb code 9iti). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the NAV1.7 with Mutations That Eliminate BETA1 Binding, PDB code: 9iti:

Sodium binding site 1 out of 1 in the NAV1.7 with Mutations That Eliminate BETA1 Binding


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of NAV1.7 with Mutations That Eliminate BETA1 Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Na2004 b:30.0 occ:1.00 OE2 A:GLU930 2.9 22.8 1.0 CB A:GLU930 3.3 22.8 1.0 CB A:TYR362 3.8 20.6 1.0 OD2 A:ASP361 3.8 22.0 1.0 CD A:GLU930 3.9 22.8 1.0 N A:GLU930 3.9 22.8 1.0 CG A:TYR362 3.9 20.6 1.0 OE1 A:GLU927 4.0 23.6 1.0 CG2 A:ILE929 4.0 20.4 1.0 CD A:GLU927 4.1 23.6 1.0 CG A:GLU930 4.2 22.8 1.0 CA A:GLU930 4.2 22.8 1.0 CD1 A:TYR362 4.2 20.6 1.0 CD2 A:TYR362 4.3 20.6 1.0 CB A:GLU927 4.3 23.6 1.0 NH1 A:ARG922 4.3 35.4 1.0 OE2 A:GLU927 4.5 23.6 1.0 OD1 A:ASP361 4.5 22.0 1.0 CG A:ASP361 4.5 22.0 1.0 CG A:GLU927 4.5 23.6 1.0 CA A:GLU927 4.6 23.6 1.0 N A:ILE929 4.8 20.4 1.0 N A:TRP928 4.8 22.8 1.0 C A:GLU927 4.8 23.6 1.0 CA A:TYR362 4.9 20.6 1.0 CE1 A:TYR362 5.0 20.6 1.0 OE1 A:GLU930 5.0 22.8 1.0 CE2 A:TYR362 5.0 20.6 1.0 C A:ILE929 5.0 20.4 1.0

T.Wu, X.Yang, X.Jin, N.Yan, Z.Li. Critical Role of Extracellular Loops in Differential Modulations of Ttx-Sensitive and Ttx-Resistant Na V Channels. Proc.Natl.Acad.Sci.Usa V. 122 55122 2025.
ISSN: ESSN 1091-6490
PubMed: 40768348
DOI: 10.1073/PNAS.2510355122