Sodium in PDB 8wfk: Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation

The structure of Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Fluorine	(F)	3 atoms

The binding sites of Sodium atom in the Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation (pdb code 8wfk). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation, PDB code: 8wfk:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Na703 b:30.0 occ:1.00 O A:SER317 3.4 58.1 1.0 O A:ALA63 3.7 68.8 1.0 CA A:SER317 3.9 57.5 1.0 C A:SER317 4.0 61.9 1.0 N A:GLY65 4.2 61.3 1.0 N A:GLY67 4.4 69.8 1.0 CA A:GLY65 4.4 64.7 1.0 OG A:SER317 4.4 62.8 1.0 OD1 A:ASN68 4.5 80.0 1.0 O A:TYR316 4.5 70.9 1.0 CB A:SER317 4.5 56.7 1.0 CA A:GLY67 4.5 66.7 1.0 CH2 A:TRP322 4.5 78.0 1.0 C A:GLY65 4.9 61.9 1.0 N04 A:W5O701 4.9 72.3 1.0 C A:ALA63 4.9 64.3 1.0 C09 A:W5O701 4.9 73.8 1.0 N A:SER317 4.9 57.2 1.0 N A:LEU66 5.0 59.7 1.0

Sodium binding site 2 out of 2 in the Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Human Glycine Transporter 1 in Complex with SSR504734 in Outward Facing Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Na704 b:30.0 occ:1.00 O A:VAL64 2.1 70.8 1.0 O A:LEU414 2.3 61.6 1.0 CA A:GLY65 2.9 64.7 1.0 OG1 A:THR418 3.0 62.6 1.0 C A:VAL64 3.1 64.8 1.0 O A:GLY61 3.2 67.0 1.0 N A:GLY65 3.4 61.3 1.0 C A:LEU414 3.4 61.8 1.0 C A:GLY65 4.0 61.9 1.0 CA A:LEU414 4.0 50.8 1.0 N A:THR418 4.1 66.0 1.0 CB A:THR418 4.2 65.8 1.0 C A:GLY61 4.4 60.1 1.0 CD2 A:LEU414 4.4 64.6 1.0 CA A:VAL64 4.5 58.9 1.0 N A:GLY415 4.5 68.7 1.0 CB A:LEU414 4.5 56.2 1.0 O A:GLY65 4.5 69.8 1.0 C A:GLY417 4.6 71.6 1.0 N A:GLY417 4.7 57.9 1.0 CA A:THR418 4.7 63.8 1.0 N A:LEU66 4.7 59.7 1.0 CA A:GLY417 4.7 65.1 1.0 O A:TYR62 4.7 63.4 1.0 CA A:GLY415 4.8 62.9 1.0 N A:VAL64 4.8 66.8 1.0

Y.Wei, R.Li, Y.Meng, T.Hu, J.Zhao, Y.Gao, Q.Bai, N.Li, Y.Zhao. Transport Mechanism and Pharmacology of the Human GLYT1. Cell 2024.
ISSN: ISSN 1097-4172
PubMed: 38513663
DOI: 10.1016/J.CELL.2024.02.026