Sodium in PDB 8vvo: Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor

The structure of Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor, PDB code: 8vvo was solved by A.U.Singer, H.A.Bruce, A.Pavlenco, L.Ploder, G.Luu, L.Blazer, J.J.Adams, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.46 / 3.09
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	71.246, 90.576, 214.85, 90, 90, 90
R / Rfree (%)	25.3 / 28.9

The structure of Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Sodium atom in the Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor (pdb code 8vvo). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor, PDB code: 8vvo:

Sodium binding site 1 out of 1 in the Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of FABS1CE2-EPR1-1 in Complex with the Erythropoietin Receptor within 5.0Å range: probe atom residue distance (Å) B Occ G:Na301 b:52.8 occ:1.00 O G:THR220 3.5 72.0 1.0 OG G:SER222 3.9 72.5 1.0 C G:THR220 4.1 69.8 1.0 N G:SER222 4.3 66.2 1.0 CB G:SER222 4.5 70.1 1.0 N G:THR221 4.5 72.1 1.0 C G:THR221 4.7 70.5 1.0 CA G:THR221 4.7 70.3 1.0 CA G:THR220 4.9 72.7 1.0

H.A.Bruce, A.U.Singer, L.L.Blazer, K.Luu, L.Ploder, A.Pavlenco, I.Kurinov, J.J.Adams, S.S.Sidhu. Antigen-Binding Fragments with Improved Crystal Lattice Packing and Enhanced Conformational Flexibility at the Elbow Region As Crystallization Chaperones. Protein Sci. V. 33 E5081 2024.
ISSN: ESSN 1469-896X
PubMed: 38924648
DOI: 10.1002/PRO.5081