Sodium in PDB 7ugg: Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine

The binding sites of Sodium atom in the Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine (pdb code 7ugg). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine, PDB code: 7ugg:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine within 5.0Å range: probe atom residue distance (Å) B Occ A:Na909 b:60.0 occ:1.00 O D:GLY638 3.4 66.3 1.0 O A:GLY638 3.5 59.1 1.0 O B:GLY638 3.5 64.3 1.0 O C:GLY638 3.6 67.8 1.0 C D:GLY638 4.1 66.3 1.0 C A:GLY638 4.1 59.1 1.0 C B:GLY638 4.2 64.3 1.0 C C:GLY638 4.2 67.8 1.0 CA D:GLY638 4.3 66.3 1.0 CA A:GLY638 4.3 59.1 1.0 CA B:GLY638 4.4 64.3 1.0 CA C:GLY638 4.4 67.8 1.0

Sodium binding site 2 out of 2 in the Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of TRPV3 in Complex with the Anesthetic Dyclonine within 5.0Å range:

A.Neuberger, K.D.Nadezhdin, A.I.Sobolevsky. Structural Mechanism of TRPV3 Channel Inhibition By the Anesthetic Dyclonine. Nat Commun V. 13 2795 2022.
ISSN: ESSN 2041-1723
PubMed: 35589741
DOI: 10.1038/S41467-022-30537-8