Sodium in PDB 7sh0: Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule

The structure of Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule, PDB code: 7sh0 was solved by L.Li, M.Bouvier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	75.485, 135.949, 129.812, 90, 90.49, 90
R / Rfree (%)	20.7 / 25.4

The structure of Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Sodium atom in the Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule (pdb code 7sh0). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule, PDB code: 7sh0:

Sodium binding site 1 out of 1 in the Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Highly Selective and Potent Small Molecule within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1006 b:77.4 occ:1.00 OE2 A:GLU337 2.6 89.3 1.0 OE2 A:GLU393 2.8 108.5 1.0 OE2 A:GLU200 3.0 110.3 1.0 O25 A:GIY1002 3.4 135.7 1.0 CE1 A:HIS374 3.4 108.6 1.0 CD A:GLU393 3.6 90.5 1.0 ND2 A:ASN392 3.6 77.2 1.0 CB A:ASN392 3.6 65.3 1.0 CD A:GLU337 3.8 88.2 1.0 CD A:GLU200 3.8 93.7 1.0 OE1 A:GLU200 3.9 81.2 1.0 ND1 A:HIS374 4.0 85.5 1.0 NE2 A:HIS374 4.0 75.7 1.0 CG A:ASN392 4.1 81.3 1.0 OH A:TYR262 4.2 72.6 1.0 CG A:GLU393 4.2 72.7 1.0 OE1 A:GLU393 4.3 70.5 1.0 OE1 A:GLU337 4.4 102.9 1.0 N22 A:GIY1002 4.4 129.7 1.0 CD1 A:ILE389 4.5 71.6 1.0 CE2 A:TYR262 4.6 78.5 1.0 ZN A:ZN1001 4.7 72.5 1.0 CG A:HIS374 4.8 85.6 1.0 CD2 A:HIS374 4.8 82.0 1.0 CG A:GLU337 4.8 73.5 1.0 CZ A:TYR262 4.9 73.0 1.0 N A:GLU393 4.9 68.6 1.0 CE2 A:PHE450 4.9 73.8 1.0 CA A:ASN392 4.9 68.8 1.0

L.Li, M.Bouvier. Crystal Structure of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) Complex with A Ligand To Be Published.