Sodium in PDB 7oiy: Crystal Structure of the Zufsp Family Member MUG105

All present enzymatic activity of Crystal Structure of the Zufsp Family Member MUG105:
3.4.19.12;

The structure of Crystal Structure of the Zufsp Family Member MUG105, PDB code: 7oiy was solved by C.Pichlo, T.Hermanns, K.Hofmann, U.Baumann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.46 / 2.05
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	88.235, 88.235, 111.011, 90, 90, 90
R / Rfree (%)	17.3 / 20.4

The binding sites of Sodium atom in the Crystal Structure of the Zufsp Family Member MUG105 (pdb code 7oiy). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the Zufsp Family Member MUG105, PDB code: 7oiy:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of the Zufsp Family Member MUG105


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Zufsp Family Member MUG105 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:62.7 occ:1.00 OG A:SER148 2.4 52.8 1.0 O A:HOH466 2.4 51.0 1.0 O A:ASN150 2.4 74.4 1.0 O A:HOH442 2.6 52.6 1.0 OG1 A:THR152 2.6 44.9 1.0 O A:HOH468 2.6 52.7 1.0 CB A:SER148 3.1 39.9 1.0 N A:THR152 3.4 70.2 1.0 O A:HOH539 3.6 50.0 1.0 C A:ASN150 3.6 79.9 1.0 CB A:THR152 3.7 60.0 1.0 CG2 A:THR152 3.9 66.6 1.0 OD1 A:ASP24 4.0 36.1 1.0 CA A:THR152 4.1 69.6 1.0 O A:SER148 4.2 73.0 1.0 C A:ASP151 4.2 82.0 1.0 CA A:ASP151 4.3 87.9 1.0 C A:SER148 4.3 52.0 1.0 CA A:SER148 4.3 56.1 1.0 OD2 A:ASP24 4.3 39.5 1.0 N A:ASP151 4.4 94.6 1.0 O A:THR152 4.5 62.1 1.0 N A:ASN150 4.6 83.2 1.0 CG A:ASP24 4.6 34.6 1.0 C A:THR152 4.6 61.6 1.0 CA A:ASN150 4.7 90.0 1.0 CG2 A:VAL155 4.8 35.5 1.0 N A:SER149 4.9 71.8 1.0 O A:HOH421 5.0 43.4 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of the Zufsp Family Member MUG105


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the Zufsp Family Member MUG105 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na301 b:66.9 occ:1.00 O B:HOH431 2.5 38.3 1.0 O B:ASN150 2.5 84.4 1.0 O B:HOH517 2.5 61.8 1.0 OG1 B:THR152 2.7 54.6 1.0 O B:HOH459 2.8 61.8 1.0 OG B:SER148 2.9 63.8 1.0 N B:THR152 3.4 112.8 1.0 CB B:SER148 3.4 52.0 1.0 O B:HOH537 3.5 61.8 1.0 C B:ASN150 3.7 92.7 1.0 CB B:THR152 3.8 79.1 1.0 OD1 B:ASP24 3.8 40.8 1.0 CA B:THR152 4.1 86.9 1.0 CG2 B:THR152 4.1 89.7 1.0 CA B:ASP151 4.2 96.5 1.0 C B:ASP151 4.2 104.2 1.0 OD2 B:ASP24 4.2 53.2 1.0 O B:THR152 4.4 72.6 1.0 O B:SER148 4.4 68.5 1.0 N B:ASP151 4.4 93.0 1.0 CG B:ASP24 4.5 42.9 1.0 C B:SER148 4.5 77.0 1.0 C B:THR152 4.6 69.9 1.0 O B:HOH413 4.6 57.5 1.0 CA B:SER148 4.6 77.5 1.0 N B:ASN150 4.8 105.8 1.0 O B:HOH422 4.8 39.8 1.0 CG2 B:VAL155 4.9 40.3 1.0 CA B:ASN150 4.9 110.0 1.0 O B:HOH545 4.9 58.6 1.0

T.Hermanns, C.Pichlo, U.Baumann, K.Hofmann. A Structural Basis For the Diverse Linkage Specificities Within the Zufsp Deubiquitinase Family. Nat Commun V. 13 401 2022.
ISSN: ESSN 2041-1723
PubMed: 35058438
DOI: 10.1038/S41467-022-28049-6