Sodium in PDB 7ogj: Crystal Structure of Human METTL1 in Complex with Sah

All present enzymatic activity of Crystal Structure of Human METTL1 in Complex with Sah:
2.1.1.33;

The structure of Crystal Structure of Human METTL1 in Complex with Sah, PDB code: 7ogj was solved by F.Nai, R.K.Bedi, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.92 / 1.59
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.57, 80.46, 138.23, 90, 90, 90
R / Rfree (%)	19.5 / 21.5

The binding sites of Sodium atom in the Crystal Structure of Human METTL1 in Complex with Sah (pdb code 7ogj). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Human METTL1 in Complex with Sah, PDB code: 7ogj:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Human METTL1 in Complex with Sah


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human METTL1 in Complex with Sah within 5.0Å range: probe atom residue distance (Å) B Occ A:Na308 b:24.5 occ:1.00 O A:HOH551 2.9 34.0 1.0 N A:GLY59 3.0 21.8 1.0 O A:HOH456 3.1 22.9 1.0 N A:GLU209 3.1 22.3 1.0 N A:GLY58 3.6 25.2 1.0 CA A:THR208 3.6 21.2 1.0 C A:TYR57 3.6 25.2 1.0 CA A:GLY59 3.6 21.9 1.0 CG A:GLU209 3.6 31.4 1.0 CB A:TYR57 3.7 26.3 1.0 N A:TYR57 3.8 23.3 1.0 CB A:THR208 3.8 22.1 1.0 CA A:TYR57 3.8 26.4 1.0 C A:THR208 3.8 21.4 1.0 CB A:GLU209 4.0 27.2 1.0 O A:HOH513 4.0 37.6 1.0 O A:TYR57 4.1 25.7 1.0 CA A:GLU209 4.1 24.2 1.0 OXT A:SAH301 4.1 21.0 1.0 C A:GLY58 4.1 25.8 1.0 CA A:GLY58 4.4 24.9 1.0 O A:CYS55 4.5 21.8 1.0 CG2 A:THR208 4.6 22.4 1.0 O A:SER207 4.6 24.2 1.0 O A:HOH435 4.6 26.2 1.0 CD A:GLU209 4.7 39.6 1.0 O A:HOH417 4.8 32.6 1.0 C A:GLY59 4.8 22.6 1.0 C A:SAH301 4.8 20.4 1.0 OE2 A:GLU209 4.8 46.8 1.0 C A:GLY56 4.8 24.4 1.0 N A:THR208 4.9 22.6 1.0 CG A:TYR57 4.9 28.1 1.0 N A:LEU60 5.0 20.5 1.0 OG1 A:THR208 5.0 20.0 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Human METTL1 in Complex with Sah


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Human METTL1 in Complex with Sah within 5.0Å range: probe atom residue distance (Å) B Occ B:Na308 b:30.2 occ:1.00 O4 B:SO4306 2.6 47.9 1.0 O B:HOH454 2.7 41.4 1.0 N B:ARG144 3.1 19.6 1.0 O3 B:SO4306 3.2 41.5 1.0 S B:SO4306 3.5 54.0 1.0 CG B:ARG144 3.6 25.7 1.0 CB B:ARG144 3.6 24.1 1.0 CA B:TRP143 3.7 21.2 1.0 CG B:MET112 3.7 35.8 1.0 O B:LYS142 3.7 26.7 1.0 C B:TRP143 3.8 19.8 1.0 O B:HOH606 3.9 40.3 1.0 CA B:ARG144 3.9 18.8 1.0 CD1 B:TRP143 3.9 22.0 1.0 CB B:MET112 4.0 30.5 1.0 O2 B:SO4306 4.3 47.1 1.0 C B:LYS142 4.3 26.0 1.0 SD B:MET112 4.3 33.9 1.0 N B:TRP143 4.4 22.3 1.0 NE B:ARG144 4.4 37.9 1.0 O1 B:SO4306 4.6 57.1 1.0 CD B:ARG144 4.6 39.3 1.0 CG B:TRP143 4.8 21.3 1.0 CB B:TRP143 4.8 20.3 1.0 C B:ARG144 4.9 17.6 1.0 NE1 B:TRP143 5.0 22.0 1.0

F.Nai, R.K.Bedi, A.Caflisch. Crystal Structure of Human METTL1 in Complex with Sah To Be Published.