Sodium in PDB 7ntn: The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution

The structure of The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution, PDB code: 7ntn was solved by E.Davydova, R.Janowski, M.Witzenberger, D.Niessing, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.48 / 2.02
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	131.45, 131.45, 131.45, 90, 90, 90
R / Rfree (%)	20.5 / 25.1

The structure of The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Sodium atom in the The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution (pdb code 7ntn). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution, PDB code: 7ntn:

Sodium binding site 1 out of 1 in the The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Structure of Rrm Domain of Human TRMT2A at 2 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na208 b:66.8 occ:1.00 CL A:CL207 2.9 71.4 1.0 CD2 A:HIS83 3.7 85.7 1.0 CB A:HIS83 3.8 67.5 1.0 N A:HIS83 3.8 41.9 1.0 CB A:PRO81 3.9 35.8 1.0 CG A:HIS83 4.1 81.0 1.0 N A:ARG82 4.2 32.6 1.0 CA A:HIS83 4.3 50.0 1.0 CL A:CL206 4.4 90.8 1.0 C A:PRO81 4.5 35.4 1.0 CA A:PRO81 4.6 33.5 1.0 C A:HIS83 4.8 48.7 1.0 C A:ARG82 4.9 39.5 1.0 NE2 A:HIS83 5.0 85.5 1.0

M.A.Margreiter, M.Witzenberger, Y.Wasser, E.Davydova, R.Janowski, J.Metz, P.Habib, S.E.M.Sahnoun, C.Sobisch, B.Poma, O.Palomino-Hernandez, M.Wagner, T.Carell, N.Jon Shah, J.B.Schulz, D.Niessing, A.Voigt, G.Rossetti. Small-Molecule Modulators of TRMT2A Decrease Polyq Aggregation and Polyq-Induced Cell Death. Comput Struct Biotechnol J V. 20 443 2022.
ISSN: ESSN 2001-0370
PubMed: 35070167
DOI: 10.1016/J.CSBJ.2021.12.029