Sodium in PDB 7n5c: 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond

The structure of 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond, PDB code: 7n5c was solved by C.Szeto, S.Gras, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.14 / 1.87
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.086, 74.113, 114.295, 90, 99.34, 90
R / Rfree (%)	20.4 / 23.3

The binding sites of Sodium atom in the 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond (pdb code 7n5c). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond, PDB code: 7n5c:

Sodium binding site 1 out of 1 in the 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of 6218 Tcr in Complex with H2DB Pa with An Engineered Tcr-Pmhc Disulfide Bond within 5.0Å range: probe atom residue distance (Å) B Occ E:Na301 b:32.3 occ:1.00 CE E:MET15 2.3 49.4 1.0 N E:THR96 3.0 26.4 1.0 CA E:LYS95 3.5 25.6 1.0 OG1 E:THR96 3.6 29.1 1.0 C E:LYS95 3.7 28.9 1.0 CB E:LYS95 3.8 26.9 1.0 CG2 E:THR96 3.9 33.4 1.0 SD E:MET15 4.0 51.8 1.0 CB E:THR96 4.1 34.4 1.0 CB E:MET15 4.1 36.5 1.0 CA E:THR96 4.1 26.4 1.0 CG E:LYS95 4.3 31.7 1.0 O E:ALA94 4.6 28.8 1.0 CG E:MET15 4.6 43.5 1.0 N E:LYS95 4.7 25.9 1.0 O E:LYS95 4.9 25.4 1.0 CD E:LYS95 4.9 41.4 1.0

C.Szeto, P.Zareie, R.C.Wirasinha, J.B.Zhang, A.T.Nguyen, A.Riboldi-Tunnicliffe, N.L.La Gruta, S.Gras, S.R.Daley. Covalent Tcr-Peptide-Mhc Interactions Induce T Cell Activation and Redirect T Cell Fate in the Thymus. Nat Commun V. 13 4951 2022.
ISSN: ESSN 2041-1723
PubMed: 35999236
DOI: 10.1038/S41467-022-32692-4